Abstract The AACR Project GENIE is an international data-sharing consortium focused on
generating an evidence base for precision cancer medicine by integrating clinical-grade …

Abstract The American Association for Cancer Research (AACR) Project Genomics
Evidence Neoplasia Information Exchange (GENIE) is an international pan-cancer registry …

Early successes in identifying and targeting individual oncogenic drivers, together with the
increasing feasibility of sequencing tumor genomes, have brought forth the promise of …

Precision medicine is an approach that takes into account the influence of individuals'
genes, environment, and lifestyle exposures to tailor interventions. Here, we describe the …

In this Special Series issue, Journal of Clinical Oncologypresents a systematic assessment
of cancer genomic information and its accelerating clinical impact. In the scientific literature …

Biomarker-driven cancer therapy has revolutionized precision oncology. With a better
understanding of tumor biology, tissue-agnostic targets have been characterized and …

The recent surge in high-throughput sequencing of cancer genomes has supported an
expanding molecular classification of cancer. These studies have identified putative …

Health: Make precision medicine work for cancer care | Nature Skip to main content Thank you
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The past decades have seen tremendous developments with respect to “specific”
therapeutics that target key signaling molecules to conquer cancer. The key advancements …

Current efforts in precision oncology largely focus on the benefit of genomics-guided
therapy. Yet, advances in sequencing techniques provide an unprecedented view of the …