High-generation amphiphilic Janus-dendrimers as stabilizing agents for drug suspensions

M Selin, S Nummelin, J Deleu, J Ropponen… - …, 2018 - ACS Publications
Pharmaceutical nanosuspensions are formed when drug crystals are suspended in
aqueous media in the presence of stabilizers. This technology offers a convenient way to …

[HTML][HTML] Properties and bioapplications of amphiphilic janus dendrimers: A Review

A Căta, IMC Ienașcu, MN Ştefănuț, D Roșu, OR Pop - Pharmaceutics, 2023 - mdpi.com
Amphiphilic Janus dendrimers are arrangements containing both hydrophilic and
hydrophobic units, capable of forming ordered aggregates by intermolecular noncovalent …

Modular synthesis of self-assembling Janus-dendrimers and facile preparation of drug-loaded dendrimersomes

S Nummelin, M Selin, S Legrand, J Ropponen… - Nanoscale, 2017 - pubs.rsc.org
Materials and methods aimed at the next generation of nanoscale carriers for drugs and
other therapeutics are currently in great demand. Yet, creating these precise molecular …

An emerging class of amphiphilic dendrimers for pharmaceutical and biomedical applications: Janus amphiphilic dendrimers

DR Sikwal, RS Kalhapure, T Govender - European Journal of …, 2017 - Elsevier
In recent years, a new class of dendrimer, known as Janus dendrimers (JDs), has attracted
much attention due to their different structures and properties to the conventional symmetric …

Self‐Assembly of Amphiphilic Janus Dendrimers into Mechanically Robust Supramolecular Hydrogels for Sustained Drug Release

S Nummelin, V Liljeström, E Saarikoski… - … A European Journal, 2015 - Wiley Online Library
Compounds that can gelate aqueous solutions offer an intriguing toolbox to create functional
hydrogel materials for biomedical applications. Amphiphilic Janus dendrimers with low …

Polymer-dendrimer hybrids as carriers of anticancer agents

GL Rodríguez-Acosta… - Current Drug …, 2022 - ingentaconnect.com
In recent years, polymeric materials with the ability to self-assemble into micelles have been
increasingly investigated for application in various fields, mainly in biomedicine. Micellar …

Vesicles from amphiphilic dumbbells and janus dendrimers: Bioinspired self-assembled structures for biomedical applications

S Taabache, A Bertin - Polymers, 2017 - mdpi.com
The current review focuses on vesicles obtained from the self-assembly of two types of
dendritic macromolecules, namely amphiphilic Janus dendrimers (forming dendrimersomes) …

Designing highly stable poly (sarcosine)-based telodendrimer micelles with high drug content exemplified with fulvestrant

Q Yu, RM England, A Gunnarsson, R Luxenhofer… - …, 2022 - ACS Publications
Polymeric micelles have been extensively used as nanocarriers for the delivery of
chemotherapeutic agents, aiming to improve their efficacy in cancer treatment. However, the …

Telodendrimers for physical encapsulation and covalent linking of individual or combined therapeutics

J Choi, A Moquin, E Bomal, L Na… - Molecular …, 2017 - ACS Publications
New therapeutics for glioblastoma multiforme and our ability to deliver them using efficient
nanocarriers constitute topical areas of research. We report a comparative study of …

Telodendrimers: promising architectural polymers for drug delivery

S Mejlsøe, A Kakkar - Molecules, 2020 - mdpi.com
Architectural complexity has played a key role in enhancing the efficacy of nanocarriers for a
variety of applications, including those in the biomedical field. With the continued evolution …