Glycosylation and its implications in breast cancer
DA Scott, RR Drake - Expert review of proteomics, 2019 - Taylor & Francis
Introduction: For decades, the role of glycans and glycoproteins in the progression of breast
cancer and other cancers have been evaluated. Through extensive studies focused on …
cancer and other cancers have been evaluated. Through extensive studies focused on …
A Serum Glycomics Approach to Breast Cancer Biomarkers* S
Because the glycosylation of proteins is known to change in tumor cells during the
development of breast cancer, a glycomics approach is used here to find relevant …
development of breast cancer, a glycomics approach is used here to find relevant …
Glycosylation and cancer: moving glycomics to the forefront
RR Drake - Advances in cancer research, 2015 - Elsevier
There is a long research history of studying the function of glycosylation in relation to the
development and progression of different types of cancer. The technological advances of the …
development and progression of different types of cancer. The technological advances of the …
Altered glycosylation in cancer: A promising target for biomarkers and therapeutics
Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …
Glycosylation in cancer: mechanisms and clinical implications
Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …
Glycans as cancer biomarkers
B Adamczyk, T Tharmalingam, PM Rudd - Biochimica et Biophysica Acta …, 2012 - Elsevier
BACKGROUND: Non-invasive biomarkers, such as those from serum, are ideal for disease
prognosis, staging and monitoring. In the past decade, our understanding of the importance …
prognosis, staging and monitoring. In the past decade, our understanding of the importance …
[HTML][HTML] Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
IO Potapenko, VD Haakensen, T Lüders, Å Helland… - Molecular …, 2010 - Elsevier
Glycosylation is the stepwise procedure of covalent attachment of oligosaccharide chains to
proteins or lipids, and alterations in this process have been associated with malignant …
proteins or lipids, and alterations in this process have been associated with malignant …
Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey
M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …
High-mannose glycans are elevated during breast cancer progression
MLA De Leoz, LJT Young, HJ An… - Molecular & Cellular …, 2011 - ASBMB
Alteration in glycosylation has been observed in cancer. However, monitoring glycosylation
changes during breast cancer progression is difficult in humans. In this study, we used a well …
changes during breast cancer progression is difficult in humans. In this study, we used a well …
[HTML][HTML] Hallmarks of glycosylation in cancer
J Munkley, DJ Elliott - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …
development and progression. Glycans have roles in cancer cell signalling, tumour cell …