1.1. 1 Epidemiology Allergic disease in general and asthma in particular have become an
increasing problem for public health, especially in developed countries. Epidemiologic …

Allergic asthma is a chronic, often debilitating disease which has been increasing in both
prevalence and mortality worldwide, despite increased use of currently available …

BACKGROUND Existing murine models of asthma lack many of the inflammatory and
epithelial changes that are typical of the human disease. Moreover, these models are …

Sinusitis and rhinitis are significant health care issues. Yet so little is known about the
mechanisms that cause these inflammatory disorders or even how to best treat these …

Following on from initial observations in asthma deaths [1], the inflammatory cellular infiltrate
in atopic asthma has been well characterized using bronchoscopy in conjunction with …

Exposure of non-sensitized Brown Norway (BN) rats to a 10%-ovalbumin aerosol induced
an increase in the number of neutrophils in the broncho-alveolar lavage (BAL) fluid 3 and 6 …

Asthma is a chronic debilitating disease that has been steadily increasing in prevalence and
morbidity over the last few decades. Unfortunately, despite intense efforts to identify and …

Existing models of asthma in small laboratory animals lack many of the inflammatory and
epithelial changes that are typical of the human disease. Moreover, these models are …

Allergic asthma is a complex chronic inflammatory disease of the airways, and its etiology is
multifactorial. It involves the recruitment and activation of many inflammatory and structural …

The mechanisms responsible for the development of airway remodeling in asthma are not
well understood. In the present study we evaluated to what extent differences in immune and …