Bisphosphonates are an important option for the prevention of fractures in postmenopausal
women. However, the complex instructions for the administration of oral bisphosphonates …

Bisphosphonates are the current mainstay of treatment for postmenopausal osteoporosis.
Although daily oral dosing is effective, it is associated with poor compliance, partly because …

Supplement to The Journal of Family Practice/Vol 58, No 7/July 2009 S47 www. jfponline.
com osteoporosis and Fracture Prevention: A Primary Care Issue oral bisphosphonates. 4 …

Continuation of Bisphosphonate Therapy for Osteoporosis This interactive feature about the
use of bisphosphonates to treat osteoporosis offers a case vignette accompanied by two …

Background Bisphosphonates are effective agents for the management of osteoporosis.
Their low bioavailability and low potency necessitate frequent administration on an empty …

For the majority of pharmacological interventions used for osteoporosis, the duration of
clinical trials recommended by regulatory agencies is 3 years; hence, robust data are limited …

IN THE 10 YEARS SINCE THE FIRST RESULTS FROM THE FRAC-ture Intervention Trial
(FIT) were published, 1, 2 it has been relatively straightforward to know when to start …

Bisphosphonates are widely used in the treatment of osteoporosis to reduce fracture risk.
Because of their long retention time in bone and uncommon side effects, questions have …

The amino-bisphosphonates are first-line therapy for the treatment of most patients with
osteoporosis, with proven efficacy to reduce fracture risk at the spine, hip, and other …

Bisphosphonates have been available for more than a decade. Currently, 4
bisphosphonates—alendronate, risedronate, ibandronate, and zoledronic acid—are …