Recent results on the associations between protein molecules in crystal lattices, crystal–
solution surface energy, elastic properties, strength, and spontaneous crystal cracking are …

Publisher Summary This chapter discusses various aspects of the physical chemistry of
protein crystal growth. Proteins are crystallized from aqueous solutions using methods that …

This paper introduces nucleation theory applied to crystallizing protein solutions. It is shown
that the classical approach explains the available nucleation data under most conditions …

Publisher Summary This chapter establishes a statistically viable correlation between the
available sequence of amino acids in the protein chain and the special folding of chain. This …

Protein crystallization is important for structural biology. The rate at which a protein
crystallizes is often the bottleneck in determining the protein's structure. Here, we give a …

Crystallographic studies of biological macromolecules have proved of great value in
establishing the structural foundations of biochemistry and molecular biology, and for …

Strategies for growing protein crystals have for many years been essentially empirical, the
protein, once purified to a certain homogeneity, being mixed with a selection of …

The growth of large and well ordered protein crystals remains the major obstacle in protein
structure determination by means of X-ray crystallography. One of the reasons is that the …

▪ Abstract Crystallization is necessary to obtain the three-dimensional structure of proteins
and nucleic acids; it often represents the bottleneck in structure determination. Our …

Recent data on protein crystal growth are reviewed and analyzed with an emphasis to
crystal perfection. Since relative supersaturation for protein crystal growth is typically much …