[HTML][HTML] HIV-specific B cell frequency correlates with neutralization breadth in patients naturally controlling HIV-infection
A Rouers, J Klingler, B Su, A Samri, G Laumond… - …, 2017 - thelancet.com
HIV-specific broadly neutralizing antibodies (bnAbs) have been isolated from patients with
high viremia but also from HIV controllers that repress HIV-1 replication. In these elite …
high viremia but also from HIV controllers that repress HIV-1 replication. In these elite …
[HTML][HTML] Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth
A minor subset of individuals infected with HIV-1 develop antibody neutralization breadth
during the natural course of the infection, often linked to chronic, high-level viremia. Despite …
during the natural course of the infection, often linked to chronic, high-level viremia. Despite …
Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers
JI Lai, AF Licht, AS Dugast, T Suscovich, I Choi… - Journal of …, 2014 - Am Soc Microbiol
Understanding the coordination between humoral and cellular immune responses may be
the key to developing protective vaccines, and because genetic studies of long-term HIV-1 …
the key to developing protective vaccines, and because genetic studies of long-term HIV-1 …
Maintenance of HIV-specific memory B-cell responses in elite controllers despite low viral burdens
CM Buckner, L Kardava, X Zhang… - The Journal of …, 2016 - academic.oup.com
Human immunodeficiency virus (HIV)–specific B-cell responses in infected individuals are
maintained by active HIV replication. Suppression of viremia by antiretroviral therapy (ART) …
maintained by active HIV replication. Suppression of viremia by antiretroviral therapy (ART) …
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
Some HIV-1–infected patients develop broad and potent HIV-1 neutralizing antibodies
(bNAbs) that when passively transferred to mice or macaques can treat or prevent infection …
(bNAbs) that when passively transferred to mice or macaques can treat or prevent infection …
Potency of HIV-2-specific antibodies increase in direct association with loss of memory B cells
C Rocha, J Duarte, P Borrego, R Calado, JM Marcelino… - AIDS, 2017 - journals.lww.com
Potent HIV-neutralizing antibodies are critical for vaccination and viral reservoir control. High
levels of neutralizing antibodies characterize HIV-2 infection, a naturally occurring model of …
levels of neutralizing antibodies characterize HIV-2 infection, a naturally occurring model of …
[HTML][HTML] Circulating CXCR5+ CXCR3+ PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth
E Martin-Gayo, J Cronin, T Hickman, Z Ouyang… - JCI insight, 2017 - ncbi.nlm.nih.gov
HIV-1–specific broadly neutralizing antibodies (bnAbs) typically develop in individuals with
continuous high-level viral replication and increased immune activation, conditions that …
continuous high-level viral replication and increased immune activation, conditions that …
[HTML][HTML] Polyclonal broadly neutralizing antibody activity characterized by Cd4 binding site and V3-glycan antibodies in a subset of hiv-1 virus controllers
TE Nyanhete, RJ Edwards, CC LaBranche… - Frontiers in …, 2021 - frontiersin.org
Broadly neutralizing antibodies (bNAbs), known to mediate immune control of HIV-1
infection, only develop in a small subset of HIV-1 infected individuals. Despite being …
infection, only develop in a small subset of HIV-1 infected individuals. Despite being …
[HTML][HTML] Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
V Lorin, I Fernández, G Masse-Ranson… - Journal of Experimental …, 2022 - rupress.org
Decrypting the B cell ontogeny of HIV-1 broadly neutralizing antibodies (bNAbs) is
paramount for vaccine design. Here, we characterized IgA and IgG bNAbs of three distinct B …
paramount for vaccine design. Here, we characterized IgA and IgG bNAbs of three distinct B …
B‐cell responses to HIV infection
S Moir, AS Fauci - Immunological reviews, 2017 - Wiley Online Library
The induction of neutralizing antibodies directed against the human immunodeficiency virus
(HIV) has received considerable attention in recent years, in part driven by renewed interest …
(HIV) has received considerable attention in recent years, in part driven by renewed interest …