The aim of this study was to investigate the effect of low generation (G0–G3)
ethylenediamine (EDA) core poly (amidoamine)(PAMAM) dendrimers on the aqueous …

In the present study we investigated the effect of ethylenediamine (EDA) core
polyamidoamine (PAMAM) dendrimers on the aqueous solubility of nicotinic acid. The …

The objective of this study was to determine the effect of ethylenediamine core PAMAM
dendrimers, on the release of nifedipine suspended in aqueous gels and to correlate …

The solubility of the hydrophobic drug ibuprofen has been compared in an aqueous solution
of polyamidoamine (PAMAM) G4 dendrimer and sodium dodecyl sulphate (SDS). The …

Ketoprofen is a non-steroidal anti-inflammatory drug which is not freely soluble in water and
creates gastrointestinal problems. In the present study we investigated the potential of …

Dendrimers today are known for their three dimensional, monodispersed, highly branched,
macromolecular nano-scopic architecture with number of reactive end groups. Dendrimers …

Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …

The purpose of this investigation was to evaluate the performance of poly
(amidoamine)(PAMAM) dendrimers, with three different surface groups, to be used as drug …

Relationships of electrostatic interaction and encapsulation between poly
(amidoamine)(PAMAM) dendrimers and negatively charged drug molecules have been …

Approximately 40% of newly developed drugs are rejected by the pharmaceutical industry
and will never benefit a patient because of low water solubility. Another 17% of launched …