Although there is a body of literature on the therapeutic efficacy of sleep deprivation (SD)
there are only a few investigations in which the relevance of antidepressive medication for …

To test the hypothesis that the antidepressant effects of total sleep deprivation (TSD) are
linked to the serotonergic and/or noradrenergic system the authors carried out a double …

The literature suggests that sleep deprivation can potentiate the effect of antidepressant
medication in depressed patients. However, the clinical efficacy of sleep deprivation has not …

Since the discovery of the antidepressant effects of total sleep deprivation (TSD) in
depressives, the relevance of antidepressant medication (ADM) for the clinical effects of TSD …

Total sleep deprivation (TSD) exerts beneficial but only transient effects on mood in
approximately 60% of the patients with a major depressive disorder (MDD). The positive …

Sixty depressed patients were treated first with sleep deprivation (SD) and afterwards with
clomipramine or maprotiline. A statistically significant correlation was found between the …

Thirty depressed patients were deprived of sleep during the second half of the night after
they were characterized according to their Research Diagnostic Criteria diagnosis, severity …

Background: There are clinical as well as experimental indications that–contrary to what is
generally assumed—late partial sleep deprivation (LPSD) is not as effective as total sleep …

The antidepressant response to partial sleep deprivation early in the night (PSD‐E) was
compared with the response to partial sleep deprivation late in the night (PSD‐L) in 16 drug …

The mood-improving effect of sleep deprivation (SD) in depression is even today still not
fully understood. Despite the fact that mood and cognitive functions are lowered by …