[HTML][HTML] The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes

IL de la Serna, Y Ohkawa, C Higashi, C Dutta… - Journal of Biological …, 2006 - ASBMB
The microphthalmia transcription factor (Mitf) activates melanocyte-specific gene expression,
is critical for survival and proliferation of melanocytes during development, and has been …

Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival

HR Widlund, DE Fisher - Oncogene, 2003 - nature.com
The microphthalamia-associated transcription factor (MITF) is an integral transcriptional
regulator in melanocyte, the lineage from which melanoma cells originate. This basic-helix …

MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines

LT Bemis, R Chen, CM Amato, EH Classen… - Cancer research, 2008 - AACR
Micropthalmia-associated transcription factor (MITF) is the master regulator of melanocyte
development, survival, and function. Frequent alteration in the expression of MITF is …

[HTML][HTML] Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a

K Takeda, K Yasumoto, R Takada, S Takada… - Journal of Biological …, 2000 - ASBMB
Microphthalmia-associated transcription factor (Mitf) plays a critical role in the development
of neural crest-derived melanocytes. Here, we show that exogenously added Wnt-3a …

Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer

R Haq, DE Fisher - Journal of Clinical Oncology, 2011 - ascopubs.org
Members of the micropthalmia (MiT) family of transcription factors (MITF, TFE3, TFEB, and
TFEC) are physiologic regulators of cell growth, differentiation, and survival in several tissue …

Microphthalmia transcription factor: not a sensitive or specific marker for the diagnosis of desmoplastic melanoma and spindle cell (non-desmoplastic) melanoma

SR Granter, KN Weilbaecher, C Quigley… - The American journal …, 2001 - journals.lww.com
Microphthalmia transcription factor (Mitf), a melanocytic nuclear protein critical for the
embryonic development and postnatal viability of melanocytes, is a master lineage regulator …

[HTML][HTML] Regulation of the microphthalmia-associated transcription factor gene by the Waardenburg syndrome type 4 gene, SOX10

C Verastegui, K Bille, JP Ortonne, R Ballotti - Journal of Biological …, 2000 - ASBMB
The absence of melanocytes from the cochlea and epidermis is responsible of deafness and
hypopigmentation, two symptoms shared by the four Waardenburg syndrome (WS) …

β-Catenin–induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

HR Widlund, MA Horstmann, ER Price, J Cui… - The Journal of cell …, 2002 - rupress.org
The transcription factor Microphthalmia-associated transcription factor (MITF) is a lineage-
determination factor, which modulates melanocyte differentiation and pigmentation. MITF …

Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily …

M Rehli, N Den Elzen, AI Cassady, MC Ostrowski… - Genomics, 1999 - Elsevier
The microphthalmia-TFE (MiT) subfamily of basic helix-loop-helix leucine zipper (bHLH-ZIP)
transcription factors, including TFE3, TFEB, TFEC, and Mitf, has been implicated in the …

Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9

W Xu, L Gong, MM Haddad, O Bischof, J Campisi… - Experimental cell …, 2000 - Elsevier
The basic helix-loop-helix/leucine zipper (bHLH/ZIP) microphthalmia-associated
transcription factor (MITF) regulates transcription of genes encoding enzymes essential for …