Effects of capsaicin on visceral smooth muscle: a valuable tool for sensory neurotransmitter identification

L Barthó, R Benkó, R Patacchini, G Pethö… - European journal of …, 2004 - Elsevier
Studying the visceral effects of the sensory stimulant capsaicin is a useful and relatively
simple tool of neurotransmitter identification and has been used for this purpose for …

Specific motor effects of capsaicin on human jejunum

CA Maggi, R Patacchini, P Santicioli, S Giuliani… - European journal of …, 1988 - Elsevier
Capsaicin (1 μM) produced a biphasic effect on the motility of longitudinal muscle strips from
human jejunum eg an initial inhibitory effect on nerve-mediated contractions followed by a …

Evidence for the involvement of ATP, but not of VIP/PACAP or nitric oxide, in the excitatory effect of capsaicin in the small intestine

L Barthó, Z Lázár, L Lénárd Jr, R Benkó, G Tóth… - European journal of …, 2000 - Elsevier
The contractile effect of capsaicin in the guinea-pig small intestine involves an activation of
enteric cholinergic neurons. Our present data show that the P2 purinoceptor antagonist …

Tachykinin receptors are involved in the “local efferent” motor response to capsaicin in the guinea-pig small intestine and oesophagus

L Barthó, L Lenard Jr, R Patacchini, V Halmai… - Neuroscience, 1999 - Elsevier
The sensory neuron stimulant drug capsaicin stimulates primary afferent nerve endings in
the guinea-pig small intestine, which in turn activate myenteric cholinergic neurons by an …

Several neuropeptides determine the visceromotor response to capsaicin in the guinea-pig isolated ileal longitudinal muscle

CA Maggi, R Patacchini, P Santicioli… - European journal of …, 1988 - Elsevier
Abstract Capsaicin (1 μM) produced, after an initial contraction, a depression of the field
stimulation-induced contraction of the guinea-pig isolated ileal longitudinal muscle. Both …

Forty years in capsaicin research for sensory pharmacology and physiology

J Szolcsányi - Neuropeptides, 2004 - Elsevier
Capsaicin, the pungent ingredient of chilli peppers has become a “hot” topic in neuroscience
with yearly publications over half thousand papers. It is outlined in this survey how this …

Capsaicin and primary afferent neurons: from basic science to human therapy?

CA Maggi - Journal of the autonomic nervous system, 1991 - Elsevier
We owe to N. Jancso'and his co-workers the discovery that animals treated with capsaicin
become, after an initial intense excitation of sensory neurons, unresponsive to noxious …

Capsaicin as a tool for studying sensory neuron functions

P Holzer - … Nerves and Neuropeptides in Gastroenterology: From …, 1991 - Springer
It was only by the middle of this century that the extent of the sensory innervation of visceral
organs including the gastrointestinal tract was revealed. Quantitative analysis showed that …

Tachykinin NK1 and NK2 receptors mediate atropine-resistant ileal circular muscle contractions evoked by capsaicin

L Barth'o, CA Maggi, R Patacchini - European journal of pharmacology, 1994 - Elsevier
The atropine-resistant contractile action of the sensory stimulant drug capsaicin was
examined on guinea-pig ileum circular muscle in vitro, with special regard to the …

Effect of capsaicin on gastric corpus smooth muscle of the rat in vitro

U Holzer-Petsche, H Seitz, F Lembeck - European journal of pharmacology, 1989 - Elsevier
Circular strips of the rat gastric corpus muscle were mounted in Krebs solution for isometric
tension recording. Addition of capsaicin usually led to either relaxation or contraction, but in …