The solubility behavior of drugs remains one of the most challenging aspects in formulation
development. Currently only 8% of the new molecules have both high solubility and …

Solubility is a significant physicochemical parameter that affects the absorption,
bioavailability and therapeutic effectiveness of any drug. Formulation development would …

ABSTRACT A success of formulation depends on how efficiently it makes the drug available
at the site of action. Therapeutic effectiveness of a drug depends upon the bioavailability …

The solubility behavior of drugs remains one of the most challenging aspects in the
formulation development. Although there was a great interest in solid dispersion systems …

Improving oral bioavailability of drugs those given as solid dosage forms remains a
challenge for the formulationscientists due to solubility problems. The dissolution rate could …

This article is intended to combine recent literature on solid dispersion technology for
solubility enhancement with special emphasis on mechanism responsible for the same by …

Improving oral bioavailability of drugs those given as solid dosage forms remains a
challenge for the formulation scientists due to solubility problems. The dissolution rate could …

ABSTRACT A success of formulation depends on how efficiently it makes the drug available
at the site of action. Among all the newly discovered chemical entities, about 40-45% drugs …

Solid dispersions have attracted considerable interest as an efficient means of improving the
dissolution rate and hence bioavailability of a range of hydrotrophic drugs. Â Up to 40% of …

The solubility behavior of drugs remains one of the most exigent aspects in formulation
development. With the advent of combinatorial chemistry and high throughput screening, the …