Bursting activity of striatal medium spiny neurons results from membrane potential
oscillations between a down-and an upstate that could be regulated by G-protein-coupled …

Basal ganglia processing results from a balanced activation of direct and indirect striatal
efferent pathways, which are controlled by dopamine D 1 and D 2 receptors, respectively …

Dopamine in the nucleus accumbens modulates both motivational and addictive behaviors.
Dopamine D1 and D2 receptors are generally considered to exert opposite effects at the …

The mechanism underlying dopamine D1receptor-mediated attenuation of glutamatergic
synaptic input to nucleus accumbens (NAcc) neurons was investigated in slices of rat …

Evidence for striatal A2A‐D2 heterodimers has led to a new perspective on molecular
mechanisms involved in schizophrenia and Parkinson's disease. Despite the increasing …

Adenosine A2A (A2AR) and dopamine D2 (D2R) receptors mediate the antagonism
between adenosinergic and dopaminergic transmission in striatopallidal GABAergic …

The A2AR is largely coexpressed with D2Rs and enkephalin mRNA in the striatum where it
modulates dopaminergic activity. Activation of the A2AR antagonizes D2R-mediated …

Adenosine A2A-dopamine D2 receptor interactions play a very important role in striatal
function. A2A-D2 receptor interactions provide an example of the capabilities of information …

The dopamine D3 receptor, which is highly enriched in nucleus accumbens (NAc), has been
suggested to play an important role in reinforcement and reward. To understand the …

Adenosine and dopamine (DA) strongly modulate the neuronal activity in the striatum by pre-
and postsynaptic mechanisms. As several behavioral and molecular studies indicate a …