Highlights•Furosemide is the most commonly used loop diuretic in patients with heart failure
despite data suggesting potential pharmacologic and antifibrotic benefits with torsemide.•In …

Aim: The authors assessed the comparative effectiveness of torsemide versus furosemide in
the PROTECT trial. Methods: The authors assessed the relationship between loop diuretic at …

Furosemide has historically been the primary loop diuretic in heart failure patients despite
data suggesting potential advantages with torsemide. We used the Duke Echocardiography …

Although torsemide's oral bioavailability and half-life theoretically render it a more efficient
diuretic than furosemide, the clinical outcomes of torsemide compared with furosemide …

Background Loop diuretics are recommended by clinical practice guidelines to treat volume
overload in acute decompensated heart failure (ADHF). The effectiveness of switching …

PURPOSE: Because the bioavailability of oral furosemide is erratic and often incomplete, we
tested the hypothesis that patients with heart failure who were treated with torsemide, a …

Importance Although furosemide is the most commonly used loop diuretic in patients with
heart failure, some studies suggest a potential benefit for torsemide. Objective To determine …

The health and economic burden of heart failure is significant and continues to grow each
year. Loop diuretics are an integral part of symptom management in heart failure …

Importance Differences in clinical profiles, outcomes, and diuretic treatment effects may exist
between patients with de novo heart failure (HF) and worsening chronic HF (WHF) …

Aims Loop diuretics have become a mainstay of chronic heart failure management.
Furosemide and torsemide are the two most common loop diuretics; nevertheless, there is …