[HTML][HTML] Cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: a two-centre tract of interest-based DTI analysis
Background After the demonstration of a corticoefferent propagation pattern in amyotrophic
lateral sclerosis (ALS) by neuropathological studies, this concept has been used for in vivo …
lateral sclerosis (ALS) by neuropathological studies, this concept has been used for in vivo …
[HTML][HTML] Identical patterns of cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: a tract of interest-based MRI study
HP Müller, M Gorges, R Kassubek, J Dorst… - NeuroImage: Clinical, 2018 - Elsevier
Background There is an ongoing debate whether primary lateral sclerosis (PLS) should be
regarded as an independent disease entity separate from amyotrophic lateral sclerosis …
regarded as an independent disease entity separate from amyotrophic lateral sclerosis …
[HTML][HTML] Corticoefferent pathology distribution in amyotrophic lateral sclerosis: in vivo evidence from a meta-analysis of diffusion tensor imaging data
M Gorges, K Del Tredici, J Dreyhaupt, H Braak… - Scientific reports, 2018 - nature.com
A sequential transaxonal disease spread of amyotrophic lateral sclerosis (ALS)-associated
TDP-43 pathology in four stages has been defined by post-mortem data, which have been …
TDP-43 pathology in four stages has been defined by post-mortem data, which have been …
Imaging the pathoanatomy of amyotrophic lateral sclerosis in vivo: targeting a propagation-based biological marker
J Kassubek, HP Müller, K Del Tredici, D Lulé… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective Neuropathological studies in amyotrophic lateral sclerosis (ALS) have shown a
dissemination in a regional sequence in four anatomically defined patterns. The aim of this …
dissemination in a regional sequence in four anatomically defined patterns. The aim of this …
The corticospinal tract profile in amyotrophic lateral sclerosis
This work evaluates the potential in diagnostic application of a new advanced neuroimaging
method, which delineates the profile of tissue properties along the corticospinal tract (CST) …
method, which delineates the profile of tissue properties along the corticospinal tract (CST) …
[HTML][HTML] The same cortico-efferent tract involvement in progressive bulbar palsy and in 'classical'ALS: A tract of interest-based MRI study
HP Müller, M Gorges, K Del Tredici, AC Ludolph… - NeuroImage: Clinical, 2019 - Elsevier
Background There is an ongoing debate about the concept of restricted phenotypes of
amyotrophic lateral sclerosis (ALS), including progressive bulbar palsy (PBP). Objective The …
amyotrophic lateral sclerosis (ALS), including progressive bulbar palsy (PBP). Objective The …
[HTML][HTML] Temporal and spatial progression of microstructural cerebral degeneration in ALS: A multicentre longitudinal diffusion tensor imaging study
Objective The corticospinal tract (CST) reveals progressive microstructural alterations in ALS
measurable by DTI. The aim of this study was to evaluate fractional anisotropy (FA) along …
measurable by DTI. The aim of this study was to evaluate fractional anisotropy (FA) along …
Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis
M Sach, G Winkler, V Glauche, J Liepert, B Heimbach… - Brain, 2004 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative system disorder
affecting both upper and lower motor neurons. Despite supportive electrophysiological …
affecting both upper and lower motor neurons. Despite supportive electrophysiological …
Diffusion Tensor Imaging in Amyotrophic Lateral Sclerosis—Increased Sensitivity with Optimized Region-of-Interest Delineation
Purpose Diagnosis of amyotrophic lateral sclerosis (ALS) can be difficult from clinical
symptoms alone. Diffusion tensor imaging (DTI) has been suggested as an adjunct …
symptoms alone. Diffusion tensor imaging (DTI) has been suggested as an adjunct …
Multimodal tract-based analysis in ALS patients at 7T: a specific white matter profile?
E Verstraete, DL Polders, RCW Mandl… - … lateral sclerosis and …, 2014 - Taylor & Francis
Our objective was to explore the value of additional MR contrasts in elucidating the
decrease in fractional anisotropy (FA) as has been observed in the corticospinal tracts (CST) …
decrease in fractional anisotropy (FA) as has been observed in the corticospinal tracts (CST) …