Rab3a deletion reduces vesicle docking and transmitter release at the mouse diaphragm synapse

WL Coleman, CA Bill, M Bykhovskaia - Neuroscience, 2007 - Elsevier
Rab3a is a small GTP binding protein associated with presynaptic vesicles that is thought to
regulate vesicle targeting to active zones. Although this rab3a function implies that vesicle …

Rab3A deletion selectively reduces spontaneous neurotransmitter release at the mouse neuromuscular synapse

MS Sons, JJ Plomp - Brain research, 2006 - Elsevier
Rab3A is a synaptic vesicle-associated GTP-binding protein thought to be involved in
modulation of presynaptic transmitter release through regulation of vesicle trafficking and …

Rab3a-mediated vesicle recruitment regulates short-term plasticity at the mouse diaphragm synapse

WL Coleman, M Bykhovskaia - Molecular and Cellular Neuroscience, 2009 - Elsevier
Rab3a is a small GTP-binding protein associated with presynaptic vesicles. We have
measured the releasable pool in the neuromuscular junction of Rab3a (−) mice by …

Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction

M Tanaka, J Miyoshi, H Ishizaki, A Togawa… - Molecular biology of …, 2001 - Am Soc Cell Biol
The Rab3 small G protein family consists of four members, Rab3A,-3B,-3C, and-3D. Of these
members, Rab3A regulates Ca2+-dependent neurotransmitter release. These small G …

Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release

OM Schlüter, E Schnell, M Verhage… - Journal of …, 1999 - Soc Neuroscience
Rab3A and rab3C are GTP-binding proteins of synaptic vesicles that regulate vesicle
exocytosis. Rabphilin is a candidate rab3 effector at the synapse because it binds to rab3s in …

Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals

AGM Leenders, FHL da Silva… - Molecular biology of …, 2001 - Am Soc Cell Biol
The rab family of GTP-binding proteins regulates membrane transport between intracellular
compartments. The major rab protein in brain, rab3A, associates with synaptic vesicles …

Actions of Rab27B‐GTPase on mammalian central excitatory synaptic transmission

ER Arias‐Hervert, N Xu, M Njus… - Physiological …, 2020 - Wiley Online Library
Members of the Rab3 gene family are considered central to membrane trafficking of synaptic
vesicles at mammalian central excitatory synapses. Recent evidence, however, indicates …

A complete genetic analysis of neuronal Rab3 function

OM Schlüter, F Schmitz, R Jahn… - Journal of …, 2004 - Soc Neuroscience
Rab3A, Rab3B, Rab3C, and Rab3D are closely related GTP-binding proteins of synaptic
vesicles that may function in neurotransmitter release. We have produced knock-out (KO) …

Coordination of synaptic vesicle trafficking and turnover by the Rab35 signaling network

P Sheehan, CL Waites - Small GTPases, 2019 - Taylor & Francis
Rab35 and the Rab35 network of GAPs, GEFs, and effectors are important regulators of
membrane trafficking for a variety of cellular processes, from cytokinesis and phagocytosis to …

Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles

ML Nonet, JE Staunton, MP Kilgard… - Journal of …, 1997 - Soc Neuroscience
Rab molecules regulate vesicular trafficking in many different exocytic and endocytic
transport pathways in eukaryotic cells. In neurons, rab3 has been proposed to play a crucial …