Measurement of urea in human serum by isotope dilution mass spectrometry: a reference procedure
A Kessler, L Siekmann - Clinical Chemistry, 1999 - academic.oup.com
Background: A reference measurement procedure is needed to demonstrate the traceability
of results of urea measurements in human serum. We developed a measurement procedure …
of results of urea measurements in human serum. We developed a measurement procedure …
Determination of serum urea by isotope dilution mass spectrometry as a candidate definitive method
MJ Welch, A Cohen, HS Hertz, FC Ruegg… - Analytical …, 1984 - ACS Publications
An Isotope dilution mass spectrometrlc (ID/MS) method for serum urea Is described. The
method utilizes urea-180 as the labeled Internal standard and Involves Isolation of urea from …
method utilizes urea-180 as the labeled Internal standard and Involves Isolation of urea from …
Assay of stable isotope labelled urea in biological fluids by selected ion monitoring
JE Nelson, TI Ruo - Clinica chimica acta, 1988 - Elsevier
A selected ion-monitoring method, incorporating an internal standard, was developed to
allow the direct and simultaneous measurement of stable isotopelabelled urea and …
allow the direct and simultaneous measurement of stable isotopelabelled urea and …
Determination of Urea Kinetics by Isotope Dilution with [13C]Urea and Gas Chromatography–isotope Ratio Mass Spectrometry (GC–IRMS) Analysis
WD Kloppenburg, BG Wolthers, F Stellaard… - Clinical …, 1997 - portlandpress.com
1. Stable urea isotopes can be used to study urea kinetics in humans. The use of stable urea
isotopes for studying urea kinetic parameters in humans on a large scale is hampered by the …
isotopes for studying urea kinetic parameters in humans on a large scale is hampered by the …
Determination of serum uric acid by isotope dilution mass spectrometry as a new candidate definitive method
P Ellerbe, A Cohen, MJ Welch, EV White - Analytical chemistry, 1990 - ACS Publications
A new Isotope dilution mass spectrometrlc method for uric acid Is described. A known weight
of [1, 3-1sN2] urlc acid Is added to a known weight of serum, and the mixture Is allowed to …
of [1, 3-1sN2] urlc acid Is added to a known weight of serum, and the mixture Is allowed to …
Determination of serum uric acid using high-performance liquid chromatography (HPLC)/isotope dilution mass spectrometry (ID-MS) as a candidate reference method
X Dai, X Fang, C Zhang, R Xu, B Xu - Journal of Chromatography B, 2007 - Elsevier
Uric acid is an important diagnostic marker of catabolism of the purine nucleosides, and
accurate measurements of serum uric acid are necessary for proper diagnosis of gout or …
accurate measurements of serum uric acid are necessary for proper diagnosis of gout or …
Measurement of serum uric acid by isotope dilution liquid chromatography tandem mass spectrometry: Modification of a candidate reference measurement method …
J Yan, H Lin, Y Xu, L Yu, S Chen, Q Zhang… - International Journal of …, 2022 - Elsevier
Uric acid is a precipitating factor for gout and renal disease, and regular monitoring of uric
acid concentration is essential for health management. Hence, accurate measurement is …
acid concentration is essential for health management. Hence, accurate measurement is …
Calibration for isotope dilution mass spectrometry—description of an alternative to the bracketing procedure
LM Thienpont, B Van Nieuwenhove… - Journal of mass …, 1996 - Wiley Online Library
A calibration method for isotope dilution mass spectrometry is presented that fully accounts
for non‐linearity of calibration functions, caused by the interference of the analyte on the m/z …
for non‐linearity of calibration functions, caused by the interference of the analyte on the m/z …
Determination of uric acid in human serum by isotope dilution-mass spectrometry. Definitive methods in clinical chemistry, III
L Siekmann - 1985 - degruyter.com
A method for the measurement of uric acid in human serum by isotope dilution-mass
spectrometry is described. The analytical procedure consists of the following Steps:(1) …
spectrometry is described. The analytical procedure consists of the following Steps:(1) …
Gas chromatography/mass spectrometric determination of [15N] urea in plasma and application to urea metabolism study
KY Tserng, SC Kalhan - Analytical Chemistry, 1982 - ACS Publications
The study of urea metabolism In humans necessitates sen-sitive methods, so that very low
Isotopic enrichments of plasma or urinary urea can be measured. A stable derivative of urea …
Isotopic enrichments of plasma or urinary urea can be measured. A stable derivative of urea …
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- isotope dilution mass spectrometry
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- chromatography tandem mass spectrometry
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- isotope ratio mass spectrometry
- isotope dilution urea kinetics
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- uric acid dilution mass
- determination of serum uric acid