Background: A reference measurement procedure is needed to demonstrate the traceability
of results of urea measurements in human serum. We developed a measurement procedure …

An Isotope dilution mass spectrometrlc (ID/MS) method for serum urea Is described. The
method utilizes urea-180 as the labeled Internal standard and Involves Isolation of urea from …

A selected ion-monitoring method, incorporating an internal standard, was developed to
allow the direct and simultaneous measurement of stable isotopelabelled urea and …

1. Stable urea isotopes can be used to study urea kinetics in humans. The use of stable urea
isotopes for studying urea kinetic parameters in humans on a large scale is hampered by the …

A new Isotope dilution mass spectrometrlc method for uric acid Is described. A known weight
of [1, 3-1sN2] urlc acid Is added to a known weight of serum, and the mixture Is allowed to …

Uric acid is an important diagnostic marker of catabolism of the purine nucleosides, and
accurate measurements of serum uric acid are necessary for proper diagnosis of gout or …

Uric acid is a precipitating factor for gout and renal disease, and regular monitoring of uric
acid concentration is essential for health management. Hence, accurate measurement is …

A calibration method for isotope dilution mass spectrometry is presented that fully accounts
for non‐linearity of calibration functions, caused by the interference of the analyte on the m/z …

A method for the measurement of uric acid in human serum by isotope dilution-mass
spectrometry is described. The analytical procedure consists of the following Steps:(1) …

The study of urea metabolism In humans necessitates sen-sitive methods, so that very low
Isotopic enrichments of plasma or urinary urea can be measured. A stable derivative of urea …