Background. Dosimetry in radionuclide therapy estimates delivered absorbed doses to
tumours and ensures that absorbed dose levels to normal organs are below tolerance …

In systemic radiation therapy, the absorbed dose distribution must be calculated from the
individual activity distribution. A computer code has been developed for the conversion of an …

A general method is presented for patient-specific three-dimensional (3D) absorbed dose
calculations based on quantitative SPECT activity measurements. The computational …

Accurate and precise radiation dosimetry is critical for the successful therapeutic application
of systemically administered radionuclides, including, of course, radionuclides in the form of …

The evaluation of radiation absorbed doses in tumorous and healthy tissues is of increasing
interest for 90Y microsphere radioembolization of liver malignancies. The objectives of this …

A practical quantitative single photon emission computed tomographic (SPECT) technique
based on an empirical threshold analysis permits accurate measurements in humans of …

131I radionuclide therapy studies have not shown a strong relationship between tumor
absorbed dose and response, possibly due to inaccuracies in activity quantification and …

A number of factors impact the accuracy of activity quantitation in planar and single photon
emission computed tomographic (SPECT) imaging. Two important such factors are …

A general method is presented for patient-specific 3-dimensional absorbed dose
calculations based on quantitative SPECT activity measurements. Methods: The …

Radiation dose calculations in nuclear medicine depend on quantification of activity via
planar and/or tomographic imaging methods. However, both methods have inherent …