[HTML][HTML] Exposure to perfluoroalkyl chemicals and cardiovascular disease: experimental and epidemiological evidence

A Meneguzzi, C Fava, M Castelli… - Frontiers in endocrinology, 2021 - frontiersin.org
Polyfluoro-and perfluoro–alkyl substances (PFAS) are organic chemicals extensively used
worldwide for industry and consumer products. Due to their chemical stability, PFAS …

Serum polyfluoroalkyl chemicals are associated with risk of cardiovascular diseases in national US population

M Huang, J Jiao, P Zhuang, X Chen, J Wang… - Environment …, 2018 - Elsevier
Abstract Background Perfluoroalkyl chemicals (PFCs) as possible cardiovascular disrupters
are universally detected in humans. However, evidence from epidemiological studies …

Perfluoroalkyl substances and lipid concentrations in the blood: A systematic review of epidemiological studies

SH Ho, SXH Soh, MX Wang, J Ong, A Seah… - Science of The Total …, 2022 - Elsevier
Background Perfluoroalkyl substances (PFAS) are widely used synthetic aliphatic
compounds. This systematic review aims to assess PFAS associations with low-density …

[HTML][HTML] Perfluoroalkyl substances are associated with elevated blood pressure and hypertension in highly exposed young adults

G Pitter, M Zare Jeddi, G Barbieri, M Gion… - Environmental …, 2020 - Springer
Background Residents in a large area of North-Eastern Italy were exposed to perfluoroalkyl
substances (PFAS) via drinking water. Studies on the association between PFAS and blood …

[HTML][HTML] Associations of perfluoroalkyl substances (PFAS) with lipid and lipoprotein profiles

M Haug, L Dunder, PM Lind, L Lind… - Journal of exposure …, 2023 - nature.com
Background Perfluoroalkyl substances (PFAS) are man-made chemicals with unique
properties that are widely distributed in humans and the environment. Recent studies …

[HTML][HTML] Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms

ME Andersen, B Hagenbuch, U Apte, JC Corton… - Toxicology, 2021 - Elsevier
Serum concentrations of cholesterol are positively correlated with exposure to
perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) in humans. The …

Associations between per-and polyfluoroalkyl substances exposures and blood lipid levels among adults—a meta-analysis

B Liu, L Zhu, M Wang, Q Sun - Environmental health perspectives, 2023 - ehp.niehs.nih.gov
Background: Associations between per-and polyfluoroalkyl substances (PFAS) and blood
lipid levels in humans were mixed. Objectives: The objective of this meta-analysis was to …

A review of cardiovascular effects and underlying mechanisms of legacy and emerging per-and polyfluoroalkyl substances (PFAS)

ZJ Wen, YJ Wei, YF Zhang, YF Zhang - Archives of Toxicology, 2023 - Springer
Cardiovascular disease (CVD) poses the leading threats to human health and life, and their
occurrence and severity are associated with exposure to environmental pollutants. Per-and …

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?

S Fragki, H Dirven, T Fletcher… - Critical reviews in …, 2021 - Taylor & Francis
Associations between per-and polyfluoroalkyl substances (PFASs) and increased blood
lipids have been repeatedly observed in humans, but a causal relation has been debated …

Changes in serum levels of perfluoroalkyl substances during a 10-year follow-up period in a large population-based cohort

J Stubleski, S Salihovic, L Lind, PM Lind… - Environment …, 2016 - Elsevier
Poly-and perfluoroalkyl substances (PFASs) are a group of man-made fluorinated chemicals
which have, at background levels, been associated with negative health effects in humans …