[HTML][HTML] Past, present and future—β2-adrenoceptor agonists in asthma management
The β-adrenoceptor agonists (β-agonists) have been used to relieve bronchoconstriction for
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …
β-Adrenoceptor agonists and asthma—100 years of development
B Waldeck - European journal of pharmacology, 2002 - Elsevier
Inhaled β2-adrenoceptor agonists are by far the most effective and safe bronchodilators
currently available. They have not been surpassed by any other bronchodilating principle …
currently available. They have not been surpassed by any other bronchodilating principle …
β2 Agonists
CK Billington, RB Penn, IP Hall - … and Therapeutics of Asthma and COPD, 2017 - Springer
History suggests β agonists, the cognate ligand of the β 2 adrenoceptor, have been used as
bronchodilators for around 5,000 years, and β agonists remain today the frontline treatment …
bronchodilators for around 5,000 years, and β agonists remain today the frontline treatment …
Airway Subsensitivity with Long-Acting β2-Agonists: Is There Cause for Concern?
BJ Lipworth - Drug Safety, 1997 - Springer
Regular treatment with both long-and short-acting β 2-agonists results in tolerance to their
bronchoprotective effects, although the relevance of this phenomenon in terms of long term …
bronchoprotective effects, although the relevance of this phenomenon in terms of long term …
β-adrenoceptor responses of the airways: for better or worse?
KJ Broadley - European journal of pharmacology, 2006 - Elsevier
β2-adrenoceptor agonists are the first-line treatment of asthma and chronic obstructive
pulmonary disease (COPD), in which a short-acting β2-adrenoceptor agonist is used as …
pulmonary disease (COPD), in which a short-acting β2-adrenoceptor agonist is used as …
Long-acting beta 2-adrenoceptor agonists: a new perspective in the treatment of asthma
CG Lofdahl, KF Chung - European Respiratory Journal, 1991 - Eur Respiratory Soc
New long-acting beta 2-adrenoceptor agonists, formoterol and salmeterol, may soon appear
in several European countries for treatment of asthma. This review examines currently …
in several European countries for treatment of asthma. This review examines currently …
Inhaled beta 2‐adrenoceptor agonists in asthma: help or hindrance?
BJ Lipworth, DG McDevitt - British journal of clinical …, 1992 - Wiley Online Library
Conventional low doses of inhaled beta 2‐adrenoceptor agonists produce effective
bronchodilation without systemic effects. Higher doses of inhaled beta 2‐adrenoceptor …
bronchodilation without systemic effects. Higher doses of inhaled beta 2‐adrenoceptor …
The beta-agonist controversy
DR Taylor, MR Sears, DW Cockcroft - Medical Clinics, 1996 - medical.theclinics.com
BACKGROUND Despite widespread use of adrenergic agents in the management of
asthma for many decades, doubts have emerged concerning the safety and efficacy of long …
asthma for many decades, doubts have emerged concerning the safety and efficacy of long …
β2‐adrenoceptor agonists: current and future direction
M Cazzola, L Calzetta… - British journal of …, 2011 - Wiley Online Library
Despite the passionate debate over the use of β2‐adrenoceptor agonists in the treatment of
airway disorders, these agents are still central in the symptomatic management of asthma …
airway disorders, these agents are still central in the symptomatic management of asthma …
Getting to the heart of asthma: Can “β blockers” be useful to treat asthma?
β2-adrenoceptor agonists are the mainstay for the acute symptomatic treatment of asthma
and provide effective bronchoprotection to a wide range of bronchoconstrictor agents …
and provide effective bronchoprotection to a wide range of bronchoconstrictor agents …