The combination of ipratropium and albuterol optimizes pulmonary function reversibility testing in patients with COPD

PM Dorinsky, C Reisner, GT Ferguson, SS Menjoge… - Chest, 1999 - Elsevier
Study objectives To determine whether the combination of ipratropium bromide and
albuterol results in greater and more consistent pulmonary function test (PFT) response …

Lung function and symptom improvement with fluticasone propionate/salmeterol and ipratropium bromide/albuterol in COPD: response by beta-agonist reversibility

ER Bleecker, A Emmett, G Crater, K Knobil… - Pulmonary pharmacology …, 2008 - Elsevier
This retrospective analysis of data from two multi-center, randomized, double-blind, parallel
group studies compared the efficacy of fluticasone propionate/salmeterol (FSC) 250/50mcg …

Extended therapy with ipratropium is associated with improved lung function in patients with COPD: a retrospective analysis of data from seven clinical trials

SI Rennard, CW Serby, M Ghafouri, PA Johnson… - Chest, 1996 - Elsevier
Objective Bronchodilators are routinely used in the long-term therapy of patients with COPD.
These drugs are generally evaluated for their short-term bronchodilatory effects. Long-term …

Diagnostic value of post-bronchodilator pulmonary function testing to distinguish between stable, moderate to severe COPD and asthma

DC Richter, JR Joubert, H Nell… - … Journal of Chronic …, 2008 - Taylor & Francis
Objective The GOLD guidelines suggest that the presence of a post-bronchodilator forced
expiratory volume in one second (FEV1)< 80% of the predicted value in combination with a …

Routine nebulized ipratropium and albuterol together are better than either alone in COPD

COMBIVENT Inhalation Solution Study Group - Chest, 1997 - Elsevier
Study objective We compared the long-term safety and efficacy of the combination
ipratropium bromide (IB) and albuterol sulfate (ALB) inhalation solution with that of each …

Bronchodilator reversibility testing in chronic obstructive pulmonary disease

PMA Calverley, PS Burge, S Spencer, JA Anderson… - Thorax, 2003 - thorax.bmj.com
Background: A limited or absent bronchodilator response is used to classify chronic
obstructive pulmonary disease (COPD) and can determine the treatment offered. The …

Is an anticholinergic agent superior to a β2-agonist in improving dyspnea and exercise limitation in COPD?

SA Blosser, SL Maxwell, MK Reeves-Hoche… - Chest, 1995 - Elsevier
Study objective To evaluate the impact of a week-long course of inhaled albuterol compared
with ipratropium on expiratory peak flow, exercise performance, and dyspnea in patients …

Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage I COPD

DE O'donnell, P Laveneziana, J Ora, KA Webb… - Thorax, 2009 - thorax.bmj.com
Background: Patients with symptoms of GOLD stage I chronic obstructive pulmonary disease
(COPD) can have significant abnormalities of ventilatory mechanics with greater exertional …

Bronchodilator responsiveness in patients with COPD

DP Tashkin, B Celli, M Decramer, D Liu… - European …, 2008 - Eur Respiratory Soc
The degree of acute improvement in spirometric indices after bronchodilator inhalation
varies among chronic obstructive pulmonary disease (COPD) patients, and depends upon …

Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial

NA Hanania, A Sharafkhaneh, B Celli, M Decramer… - Respiratory …, 2011 - Springer
Background Debate continues as to whether acute bronchodilator responsiveness (BDR)
predicts long-term outcomes in COPD. Furthermore, there is no consensus on a threshold …