Sepsis results in disruption of the endothelial glycocalyx layer and damage to the
microvasculature, resulting in interstitial accumulation of fluid and subsequently edema …

Crystalloids should still be considered as the first-choice drug for volume resuscitation in
patients with septic shock. Colloids such as albumin can be considered in some clinical …

Objective: In 2003, critical care and infectious disease experts representing 11 international
organizations developed management guidelines for fluid resuscitation in severe sepsis and …

Among critically ill adults, sepsis remains both common and lethal. In addition to antibiotics
and source control, fluid resuscitation is a fundamental sepsis therapy. The physiology of …

Fluid resuscitation continues to be recommended as the first-line resuscitative therapy for all
patients with severe sepsis and septic shock. The current acceptance of the therapy is based …

Early resuscitation of septic shock patients reduces the sepsis-related morbidity and
mortality. The main goals of septic shock resuscitation include volemic expansion …

Objectives: Hydroxyethyl starch 200 is associated with renal impairment in sepsis, but
hydroxyethyl starch 130/0.4 and gelatin are considered to be less harmful. We hypothesized …

Background Current guidelines for the management of patients with severe sepsis and
septic shock recommend crystalloids as the initial fluid solution of choice in the resuscitation …

Fluid resuscitation is an essential aspect of the management of patients with severe sepsis
and septic shock, especially in the early stages of disease. Which fluid should be used for …

Sepsis is the dysregulated immune response to severe infection that is common and lethal
among critically ill patients. Fluid administration is a common treatment for hypotension and …