Development of erythroid cells from mouse embryonic stem cells in culture: potential use for erythroid transcription factor study.

T Nakano, T Era, T Takahashi… - Leukemia …, 1997 - search.ebscohost.com
We developed an efficient differentiation induction system from mouse embryonic stem (ES)
cells into blood cells by coculture on a novel stromal cell line named OP9, in order to …

In vitro development of hematopoietic system from mouse embryonic stem cells: a new approach for embryonic hematopoiesis.

T Nakano - International journal of hematology, 1996 - europepmc.org
We developed an efficient differentiation induction system (OP9 system) from mouse
embryonic stem (ES) cell to blood cells by coculture on a novel stromal cell line, OP9. This …

[HTML][HTML] Progenitor analysis of primitive erythropoiesis generated from in vitro culture of embryonic stem cells

T Otani, T Inoue, K Tsuji-Takayama, Y Ijiri… - Experimental …, 2005 - Elsevier
OBJECTIVE: A variety of hematopoietic lineage cells have been produced from embryonic
stem (ES) cells, but their differentiation processes have not been elucidated well, especially …

[HTML][HTML] Erythroblasts derived in vitro from embryonic stem cells in the presence of erythropoietin do not express the TER-119 antigen

T Otani, S Nakamura, T Inoue, Y Ijiri… - Experimental …, 2004 - Elsevier
OBJECTIVE: In this study, we analyzed murine primitive erythropoiesis by coculturing Flk-1+
ES-derived cells with OP9 to find efficient culture conditions for erythroid cell induction. We …

A simple embryonic stem cell-based in vitro differentiation system that recapitulates early erythropoietic events in the mouse embryo

CG Kim - Korean J Zool, 1996 - koreascience.kr
An embryonic stem (ES) cell-based in vitro model system was examined to determine
whether a simple differentiation of embryoid bodies (EB) in the suspension medium is useful …

In vitro hematopoietic differentiation of murine embryonic stem cells

J Shen, CK Qu - Hematopoietic Stem Cell Protocols, 2008 - Springer
In recent years, the field of stem cells has become one of the most rapidly growing areas in
biological and medical sciences. Embryonic stem (ES) cells differentiate efficiently in vitro …

Comparison of gene expression profiles in erythroid‐like cells derived from mouse embryonic stem cells differentiated in simple and co‐culture systems

MB Boroujeni, M Salehnia, MR Valojerdi… - American journal of …, 2008 - Wiley Online Library
The feeder layer and the presence of specific growth factors are thought to induce the
differentiation of embryonic stem cells (ESCs) in culture. The aim of this study was to …

ES cells as a Model of Embryonic Hematopoiesis?

A Müller, E Dzierzak - Seminars in Developmental Biology, 1993 - Elsevier
Hematopoiesis is an extensive developmental program and differentiation process
beginning at approximately day 7 during mouse embryogenesis. Totipotential mouse …

Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells

S Carotta, S Pilat, A Mairhofer, U Schmidt, H Dolznig… - Blood, 2004 - ashpublications.org
Differentiating embryonic stem (ES) cells are an increasingly important source of
hematopoietic progenitors, useful for both basic research and clinical applications. Besides …

Enhanced hematopoietic differentiation toward erythrocytes from murine embryonic stem cells with HepG2-conditioned medium

I Fauzi, N Panoskaltsis, A Mantalaris - Stem cells and development, 2012 - liebertpub.com
Embryonic stem cell (ESC) differentiation via embryoid body (EB) formation is an
established method that generates the 3 germ layers. However, EB differentiation poses …