Although altered glycosylation has been detected in human cancer cells decades ago, only
investigations in the last years have enormously increased our knowledge about the details …

It is becoming increasingly apparent that cell surface oligosaccharides play pivotal roles as
recognition molecules in a range of cell communication and adhesion processes. Alterations …

Complex carbohydrates, which are major components of the cell membrane, perform
important functions in cell-cell and cell-extracellular matrix interactions, as well as in signal …

Aberrant glycosylation occurs in essen-tially all types of experimental and human cancers,
as has been observed for over 35 years, and many glycosyl epitopes constitute tumor …

Neoplastic transformation results in a wide variety of cellular alterations that impact the
growth, survival, and general behavior of affected tissue. Although genetic alterations …

Glycosylation defining cancer cell motility and invasiveness Page 1 Glycoconjugate Journal 20,
71–78, 2004 C 2004 Kluwer Academic Publishers. Manufactured in The Netherlands. MINI …

This review focuses on the recent advances in investigations of the role of cell surface
carbohydrates in tumor metastasis. It also summarizes the results of extensive studies of …

Introduction Glycosylation is one of the most frequentlyoccurring post-translational
modifications ofproteins. The presence of an oligosaccharide moi-ety in soluble and …

Glycosylation is catalyzed by various glycosyltransferase enzymes which are mostly located
in the Golgi apparatus in cells. These enzymes glycosylate various complex carbohydrates …

Glycosylation of proteins is one of the most important PTMs, with more than half of all human
proteins estimated to be glycosylated. It is widely known that aberrant glycosylation has …