Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics,
belonging to different therapeutic groups: macrolide and aminoglycoside, respectively …

Dendrimers are potent synergists, carriers, and delivery molecules for natural biological
products and pharmaceuticals. Staphylococcus aureus (S. aureus) infection is causing …

Purpose: The antibacterial activity of some antibiotics is specific to either Gram-positive or
Gram-negative bacteria. There are different mechanisms behind such insensitivities like …

Background: This study aimed to examine the antibacterial effect of Polyamidoamine-G4
dendrimer on Escherichia coli, Enterobacter cloacae, Bacillus subtilis and Staphylococcus …

Quinolones, an expanding class of clinically established potent antibiotics, is not freely
soluble in water which prevents the design of liquid dosage forms and restricts their use in …

The aim of this study was to investigate a range of poly (amidoamine)(PAMAM) dendrimer
generations against Gram-positive and Gram-negative skin pathogens and to determine any …

Several families of water soluble dendrimers were synthesized based on poly
(propyleneoxide) amines (Jeffamines®)(P1). P1-core and branched units were constructed …

Polyamidoamine dendrimers (PAMAM) represent a new class of hyperbranched,
monodisperse, three-dimensional polymers with unique properties, which make them very …

Materials and methods: In this research work, we explored the potential of PAMAM
dendrimers to improve the solubility of AmB. Results and discussion: The experimental …

Sulfamethoxazole (SMZ), a sulfonamide with well-known anti-bacterial properties, is not
freely soluble in water and causes problems in its clinical applications. In the present study …