In communities with high rates of consanguinity and consequently high prevalence of
recessive phenotypes, homozygosity mapping with SNP arrays is an effective approach for …

Recessively inherited phenotypes are frequent in the Palestinian population, as the result of
a historical tradition of marriages within extended kindreds, particularly in isolated villages …

Background Hearing loss or hearing impairment is a clinically and genetically
heterogeneous disorder. More than 117 genes were discovered to date in hereditary …

Background Hearing loss is a clinically and genetically heterogeneous disorder. Mutations
in the DFNB1 locus have been reported to be the most common cause of autosomal …

Hearing loss (HL) is an etiologically heterogeneous disorder that affects around 5% of the
world's population. There has been an exponential increase in the identification of genes …

Aim: To investigate the causative genetic mutations in 12 Pakistani families with
nonsyndromic or syndromic hearing loss. Methods: Mutations in the most common causative …

Hearing loss is the most common sensory disorder worldwide and affects 1 of every 500
newborns. In developed countries, at least 50% of cases are genetic, most often resulting in …

Autosomal-recessive genes are responsible for about 80% of the hereditary non-syndromic
hearing loss (NSHL) cases. In Iran, due to consanguineous marriages, NSHL is the second …

The genetic characterization of a common phenotype for an entire population reveals both
the causes of that phenotype for that place and the power of family-based, population-wide …

Hearing impairment is the most common sensory disorder, present 1 in every 500 newborns.
About 80% of genetic HL is classified as non-syndromic deafness. To date, over 115 non …