Dipyridamole shows poor and variable bioavailability after oral administration due to
pHdependent solubility, low biomembrane permeability as well as being a substrate of P …

The main purpose of current investigation is to prepare a self-microemulsifying drug delivery
system (SMEDDS) to enhance the oral bioavailability of vinpocetine, a poorly water-soluble …

Several methods are being employed to improve the oral bioavailability of lipophilic drugs
like using inert lipid vehicles such as Oils, Surfactant dispersions, Self Microemulsifying …

Self Micro-emulsifying drug delivery systems (SMEDDS) are usually used to improve the
bioavailability of hydrophobic drugs. Approximately 60-70% of new chemical entities exhibit …

Self Micro-Emulsifying drug delivery system is recent and novel approaches have been
attracted to considerable interest as an efficient means for improving solubility, dissolution …

Oral route is one of the most patient friendly routes for the most of the pharmacologically
chronic disease treatment. Nearly 40% of new drug candidates exhibit low water solubility …

Sažetak The main objective of this work was to prepare a self-micro emulsifying drug
delivery system (SMEDDS) for enhancement of oral bioavailability of domperidone, a poorly …

The aim of this study was to improve the oral absorption of loratadine, a pH-sensitive drug,
by self-microemulsifying drug delivery systems (SMEDDSs). The optimal SMEDDS was …

The objective of the present study was to determine the intestinal absorption of sulpiride
incorporated into SMEDDS by means of single-pass intestinal perfusion method (SPIP) in rat …

The study was aimed at developing a self‐microemulsifying drug delivery system (SMEDDS)
of Ibuprofen for investigating its intestinal transport behavior using the single‐pass intestinal …