1. Wood BR, Komarow L, Zolopa AR, Finkelman MA, Powderly WG, Sax PE. Test
performance of blood beta-glucan for Pneumocystis jirovecii pneumonia in patients with …

Background: HIV-infected immunological nonresponders fail to immune reconstitute despite
optimal treatment. We hypothesized that regulatory T cells (Tregs) are involved in …

Broadly reactive neutralizing antibodies are the focus of human immunodeficiency virus
(HIV) type 1 vaccine design. However, only little is known about their role in acquired …

Whether immunity against opportunistic pathogens can be fully restored by control of HIV-1
replication remains open to question. This longitudinal study was conducted to measure anti …

Objective: Two distinct hypotheses have been proposed for T-cell involvement in protection
from HIV-1 acquisition. First, HIV-1–specific memory T-cell responses generated on HIV-1 …

Current guidelines recommend initiation of antiretroviral therapy (ART) when a HIV patient
has< 200 CD4 T cells/μL. This is supported by many studies. For example, the probability of …

The role of suppressive anti-retroviral therapy (ART) in eliciting restoration of dysregulated
immune function remains unclear in HIV-1 infection. Also, due to tailoring of therapeutic …

Background: Assays to measure the induction of HIV-1-specific CD8 T-cell responses often
rely on measurements of indirect effector function such as chemokine and cytokine …

Table 1 shows the percentages of activated CD4 and CD8 T-cell subsets in LTNP,
asymptomatic progressors and uninfected controls at the baseline study. In comparison with …

Editor: Despite significant research conducted on regulatory T cells (Tregs) in HIV-1
infection, their role in HIV-1 pathogenesis is not fully elucidated. While there is evidence to …