The silencing of SFRP2 expression in ESCC is due to methylation of the gene promoter
Q Liu, YX Zhou, Hui-Wang, QX Li… - Technology in Cancer …, 2019 - journals.sagepub.com
Objective: Our aim of the study was to investigate the expression level and methylation
status of the secreted frizzled-related protein 2 in esophageal squamous cell carcinoma and …
status of the secreted frizzled-related protein 2 in esophageal squamous cell carcinoma and …
[HTML][HTML] Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma
XW Hao, ST Zhu, YL He, P Li, YJ Wang… - World journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To investigate the expression and methylation status of the secreted frizzled-related
protein 2 (SFRP2) in esophageal squamous cell carcinoma (ESCC) and explore its role in …
protein 2 (SFRP2) in esophageal squamous cell carcinoma (ESCC) and explore its role in …
Promoter methylation of the secreted frizzled‐related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma
BACKGROUND. The secreted frizzled‐related protein 1 gene (SFRP1) encodes a Wnt/β‐
catenin signaling antagonist and frequently is inactivated by promoter methylation in many …
catenin signaling antagonist and frequently is inactivated by promoter methylation in many …
Aberrant methylation of secreted frizzled‐related protein genes in esophageal adenocarcinoma and Barrett's esophagus
H Zou, JR Molina, JJ Harrington… - … journal of cancer, 2005 - Wiley Online Library
Hypermethylation of secreted frizzled‐related proteins (SFRP) genes frequently occurs with
several cancers but has not been studied in esophageal adenocarcinoma or its precursor …
several cancers but has not been studied in esophageal adenocarcinoma or its precursor …
Transcriptional silencing of secreted frizzled related protein 1 (SFRP1) by promoter hypermethylation in non-small-cell lung cancer
T Fukui, M Kondo, G Ito, O Maeda, N Sato, H Yoshioka… - Oncogene, 2005 - nature.com
Secreted frizzled related protein 1 (SFRP1) is an antagonist of the transmembrane frizzled
receptor, a component of the Wnt signaling pathway, and has been suggested to be a …
receptor, a component of the Wnt signaling pathway, and has been suggested to be a …
[HTML][HTML] Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer
The role of secreted frizzled-related protein (SFRP) genes in gastric cancer remains largely
unknown. We determined the frequency and functional significance of SFRPs …
unknown. We determined the frequency and functional significance of SFRPs …
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma
Y Meng, QG Wang, JX Wang, S Zhu, Y Jiao, P Li… - Digestive diseases and …, 2011 - Springer
Introduction The secreted frizzled-related protein 1 (SFRP1) gene, as a Wnt signaling
modulator, is frequently inactivated by promoter methylation in many tumors including …
modulator, is frequently inactivated by promoter methylation in many tumors including …
Diagnostic and prognostic value of the methylation status of secreted frizzledrelated protein 2 in colorectal cancer
D Tang, J Liu, D Wang, H Yu, Y Li… - Clinical and investigative …, 2011 - utpjournals.press
Purpose The aim of this study was to investigate the diagnostic and prognostic significance
of the methylation status of secreted frizzled-related protein 2 (SFRP2) in colorectal cancer …
of the methylation status of secreted frizzled-related protein 2 (SFRP2) in colorectal cancer …
[HTML][HTML] Secreted frizzled‑related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma
C Xiao, L Wang, L Zhu, C Zhang… - Molecular Medicine …, 2014 - spandidos-publications.com
The role of epigenetic inactivation of secreted frizzled‑related protein 2 (SFRP2) and its
functions in the development of oral squamous cell carcinoma (OSCC) remain to be …
functions in the development of oral squamous cell carcinoma (OSCC) remain to be …
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer
PK Lo, J Mehrotra, A D'Costa, MJ Fackler… - Cancer biology & …, 2006 - Taylor & Francis
Expression of Secreted frizzled related protein 1 (SFRP1), a recently identified tumor
suppressor gene encoding a WNT signaling antagonist, has been found to be frequently …
suppressor gene encoding a WNT signaling antagonist, has been found to be frequently …