A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is
supported by the high frequency of positive family history of RLS in patients affected with this …

At the outset of genetic studies in restless legs syndrome (RLS), the disorder was assumed
to be a classical monogenic disorder that runs in families. However, years of family studies …

Restless legs syndrome (RLS) is a highly familial trait with heritability estimates of about
50%. It is a polygenetic disorder in which a number of variants contribute to the phenotype …

In the 20 years since the initial consensus on a common definition for restless legs
syndrome (RLS), over 600 scientific reports on epidemiological aspects of RLS have been …

Several studies on Restless legs syndrome (RLS) have suggested a substantial genetic
contribution in the etiology of this sleep disorder. Clinical surveys of idiopathic RLS patients …

Background: Although there is a relatively high rate of occurrence of sporadic cases of
restless legs syndrome (RLS), the systematic study of family history of RLS in populations of …

Background: Restless legs syndrome (RLS) is associated with common variants in three
intronic and intergenic regions in MEIS1, BTBD9, and MAP2K5/LBXCOR1 on chromosomes …

BACKGROUND: Restless legs syndrome (RLS) is a frequent neurological disorder which is
presented in idiopathic and secondary form. Idiopathic RLS is associated with common …

Abstract Knowledge of restless legs syndrome (RLS) has greatly increased in recent years
due to the many advances that have been made in diagnosis, management and genetics …

Restless Legs syndrome (RLS) is a common sleep disorder for which the genetic
contribution remains poorly explained. In 2007, the first large scale genome wide …