Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use
Previous studies suggest epigenetic alterations may contribute to the association between
maternal prenatal depression and adverse offspring outcomes. Developmental researchers …
maternal prenatal depression and adverse offspring outcomes. Developmental researchers …
The epigenetic clock at birth: associations with maternal antenatal depression and child psychiatric problems
Objective Maternal antenatal depression may compromise the fetal developmental milieu
and contribute to individual differences in aging and disease trajectories in later life. We …
and contribute to individual differences in aging and disease trajectories in later life. We …
[HTML][HTML] Maternal prenatal anxiety and the fetal origins of epigenetic aging
MG McGill, I Pokhvisneva, AS Clappison… - Biological …, 2022 - Elsevier
Background The fetal origins of mental health is a well-established framework that currently
lacks a robust index of the biological embedding of prenatal adversity. The Pediatric-Buccal …
lacks a robust index of the biological embedding of prenatal adversity. The Pediatric-Buccal …
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants
Pregnancy can exacerbate or prompt the onset of stress-related disorders, such as post-
traumatic stress disorder (PTSD). PTSD is associated with heightened stress responsivity …
traumatic stress disorder (PTSD). PTSD is associated with heightened stress responsivity …
[PDF][PDF] Fetal sex-specific epigenetic associations with prenatal maternal depressive symptoms
Prenatal maternal mental health is a global health challenge with poorly defined biological
mechanisms. We used maternal blood samples collected during the second trimester from a …
mechanisms. We used maternal blood samples collected during the second trimester from a …
[HTML][HTML] Mother's childhood adversity is associated with accelerated epigenetic aging in pregnancy and in male newborns
Background: Adverse childhood experiences (ACEs) are correlated with accelerated
epigenetic aging, but it is not clear whether altered epigenetic aging from childhood …
epigenetic aging, but it is not clear whether altered epigenetic aging from childhood …
[HTML][HTML] Maternal psychosocial risk factors and child gestational epigenetic age in a South African birth cohort study
Accelerated epigenetic aging relative to chronological age has been found to be associated
with higher risk of mortality in adults. However, little is known about whether and how in …
with higher risk of mortality in adults. However, little is known about whether and how in …
[HTML][HTML] Maternal age at delivery is associated with an epigenetic signature in both newborns and adults
Offspring of older mothers are at increased risk of adverse birth outcomes, childhood
cancers, type 1 diabetes, and neurodevelopmental disorders. The underlying biologic …
cancers, type 1 diabetes, and neurodevelopmental disorders. The underlying biologic …
Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation
A Kotsakis Ruehlmann, S Sammallahti… - Molecular …, 2023 - nature.com
Prenatal maternal stressful life events are associated with adverse neurodevelopmental
outcomes in offspring. Biological mechanisms underlying these associations are largely …
outcomes in offspring. Biological mechanisms underlying these associations are largely …
Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways
Prenatal exposure to maternal stress, anxiety, and depression can have lasting effects on
infant development with risk of psychopathology. Although the impact of prenatal maternal …
infant development with risk of psychopathology. Although the impact of prenatal maternal …