The genetic characterization of a common phenotype for an entire population reveals both
the causes of that phenotype for that place and the power of family-based, population-wide …

Recessively inherited phenotypes are frequent in the Palestinian population, as the result of
a historical tradition of marriages within extended kindreds, particularly in isolated villages …

In communities with high rates of consanguinity and consequently high prevalence of
recessive phenotypes, homozygosity mapping with SNP arrays is an effective approach for …

Aim: To investigate the causative genetic mutations in 12 Pakistani families with
nonsyndromic or syndromic hearing loss. Methods: Mutations in the most common causative …

Deafness is a really common disorder in humans. It can begin at any age with any degree of
severity. Hereditary hearing loss is characterized by a vast genetic heterogeneity with more …

The genetic heterogeneity of congenital hearing disorders makes molecular diagnosis
expensive and time‐consuming using conventional techniques such as Sanger sequencing …

For multiple generations, much of the Arab population of Northern Israel has lived in
communities with consanguineous marriages and large families. These communities have …

Background Hearing loss is a clinically and genetically heterogeneous disorder. Mutations
in the DFNB1 locus have been reported to be the most common cause of autosomal …

Consanguineous Pakistani pedigrees segregating deafness have contributed decisively to
the discovery of 31 of the 68 genes associated with nonsyndromic autosomal recessive …

Approximately 14.5 million Pakistani individuals have a hearing loss and half of these cases
may be due to genetic causes. Though significant progress has been made in uncovering …