[HTML][HTML] Broad impact of extracellular DNA on biofilm formation by clinically isolated Methicillin-resistant and -sensitive strains of Staphylococcus aureus

S Sugimoto, F Sato, R Miyakawa, A Chiba… - Scientific reports, 2018 - nature.com
Staphylococcus aureus is a major causative agent for biofilm-associated infections. Inside
biofilms, S. aureus cells are embedded in an extracellular matrix (ECM) composed of …

Genetic and biochemical analysis of CodY-mediated cell aggregation in Staphylococcus aureus reveals an interaction between extracellular DNA and polysaccharide …

KD Mlynek, LL Bulock, CJ Stone, LJ Curran… - Journal of …, 2020 - Am Soc Microbiol
The global regulator CodY links nutrient availability to the regulation of virulence factor gene
expression in Staphylococcus aureus, including many genes whose products affect biofilm …

[HTML][HTML] Biofilm extracellular DNA enhances mixed species biofilms of Staphylococcus epidermidis and Candida albicans

M Pammi, R Liang, J Hicks, TA Mistretta, J Versalovic - BMC microbiology, 2013 - Springer
Background Polymicrobial infections are responsible for significant mortality and morbidity in
adults and children. Staphylococcus epidermidis and Candida albicans are the most …

Modulation of Staphylococcus aureus biofilm matrix by subinhibitory concentrations of clindamycin

K Schilcher, F Andreoni… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Staphylococcus aureus biofilms are extremely difficult to treat. They provide a protected
niche for the bacteria, rendering them highly recalcitrant toward host defenses as well as …

In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary …

CB Waryah, K Wells, D Ulluwishewa… - Microbial Drug …, 2017 - liebertpub.com
Staphylococcus aureus in biofilms is highly resistant to the treatment with antibiotics, to
which the planktonic cells are susceptible. This is likely to be due to the biofilm creating a …

[HTML][HTML] Biofilm Formation by Staphylococcus aureus Clinical Isolates is Differentially Affected by Glucose and Sodium Chloride Supplemented Culture Media

H Lade, JH Park, SH Chung, IH Kim, JM Kim… - Journal of clinical …, 2019 - mdpi.com
Staphylococcus aureus (S. aureus) causes persistent biofilm-related infections. Biofilm
formation by S. aureus is affected by the culture conditions and is associated with certain …

[HTML][HTML] A Review of Biofilm Formation of Staphylococcus aureus and Its Regulation Mechanism

Q Peng, X Tang, W Dong, N Sun, W Yuan - Antibiotics, 2022 - mdpi.com
Bacteria can form biofilms in natural and clinical environments on both biotic and abiotic
surfaces. The bacterial aggregates embedded in biofilms are formed by their own produced …

Differential Roles of Poly-N-Acetylglucosamine Surface Polysaccharide and Extracellular DNA in Staphylococcus aureus and Staphylococcus epidermidis Biofilms

EA Izano, MA Amarante, WB Kher… - Applied and …, 2008 - Am Soc Microbiol
Staphylococcus aureus and Staphylococcus epidermidis are major human pathogens of
increasing importance due to the dissemination of antibiotic-resistant strains. Evidence …

An electrostatic net model for the role of extracellular DNA in biofilm formation by Staphylococcus aureus

V Dengler, L Foulston, AS DeFrancesco… - Journal of …, 2015 - Am Soc Microbiol
Staphylococcus aureus is an important human pathogen that can form biofilms on various
surfaces. These cell communities are protected from the environment by a self-produced …

[HTML][HTML] Destruction of Staphylococcus aureus biofilms by combining an antibiotic with subtilisin A or calcium gluconate

JJ Liu, JY Madec, A Bousquet-Mélou, M Haenni… - Scientific reports, 2021 - nature.com
In S. aureus biofilms, bacteria are embedded in a matrix of extracellular polymeric
substances (EPS) and are highly tolerant to antimicrobial drugs. We thus sought to identify …