Evidence for renal control of urinary excretion of bile acids and bile acid sulphates in the cholestatic syndrome

JA Summerfield, J Cullen, S Barnes… - Clinical science and …, 1977 - portlandpress.com
1. The bile acids and bile acid sulphates in the urine, serum and bile of eight cholestatic
patients were studied quantitatively by gas-liquid chromatography and gas-liquid …

Disturbances of bile acid metabolism in cholestasis

A STIEHL - Clinics in gastroenterology, 1977 - Elsevier
Bile acids are formed in the liver cell, are secreted into the bile and are almost quantitatively
reabsorbed in the intestine to recirculate to the liver by the portal blood. Only a small part of …

Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis.

GP van Berge Henegouwen, KH Brandt, H Eyssen… - Gut, 1976 - gut.bmj.com
Samples of serum, bile, and urine were collected simultaneously from patients with
cholestasis of varying aetiology and from patients with cirrhosis; their bile acid composition …

Bile salt sulphates in cholestasis

A Stiehl - European Journal of Clinical Investigation, 1974 - Wiley Online Library
Bile salt sulphates were determined in serum and urine of 40 patients with severe
cholestasis due to extrahepatic obstruction, hepatitis, cirrhosis and metastases of the fiver …

Identification of bile acids in the serum and urine in cholestasis. Evidence for 6α-hydroxylation of bile acids in man

JA Summerfield, BH Billing… - Biochemical …, 1976 - portlandpress.com
In this qualitative study of the pattern of bile acid excretion in cholestasis, methods are
described for the isolation of bile acids from large volumes of urine and plasma. The bile …

Identification and quantitative determination of urinary bile acids excreted in cholestasis

P Back - Clinica Chimica Acta, 1973 - Elsevier
The monohydroxy bile acids, 3β-hydroxy-5-cholenoic acid and lithocholic acid and the
dihydroxy bile acid, ursodeoxycholic acid have been identified by means of combined gas …

Current status of cholestasis induced by monohydroxy bile acids

NB Javitt - Jaundice, 1975 - Springer
CURRENT STATUS OF CHOLESTASIS INDUCED BY MONOHYDROXY BILE ACIDS Norman
B. Javitt New York Hospital - Cornell Medical Center New Page 1 CURRENT STATUS OF …

Mechanism of cholestasis: 6. Bile acids in human livers with or without biliary obstruction

H Greim, D Trülzsch, P Czygan, J Rudick, F Hutterer… - Gastroenterology, 1972 - Elsevier
The bile acid pattern was determined in 12 surgical biopsy specimens, and in four necropsy
specimens of human liver. In normal livers, cholic acid is usually the predominant one. Only …

Serum and urinary bile acids in patients with primary biliary cirrhosis

K Samuelson, A Aly, C Johansson… - Scandinavian Journal of …, 1982 - Taylor & Francis
Serum concentrations and daily urinary excretions of unsulphated and total cholic (C) and
chenodeoxycholic (CDC) acid were determined by radioimmunoassay in 15 patients with …

Synthesis of bile acid monosulphates by the isolated perfused rat kidney

JA Summerfield, JL Gollan, BH Billing - Biochemical Journal, 1976 - portlandpress.com
Perfusion of an isolated rat kidney with labelled bile acids, in a protein-free medium, resulted
in the urinary excretion of the labelled bile acid, 3% being converted into polar metabolities …