Reservoir of bacterial exotoxin genes in the environment

V Casas, J Magbanua, G Sobrepena… - International Journal …, 2010 - Wiley Online Library
Many bacteria produce secreted virulence factors called exotoxins. Exotoxins are often
encoded by mobile genetic elements, including bacteriophage (phage). Phage can transfer …

Role of bacteriophage-encoded exotoxins in the evolution of bacterial pathogens

V Casas, S Maloy - Future microbiology, 2011 - Future Medicine
Recent advances in metagenomics research have generated a bounty of information that
provides insight into the dynamic genetic exchange occurring between bacteriophage …

Widespread occurrence of phage-encoded exotoxin genes in terrestrial and aquatic environments in Southern California

V Casas, J Miyake, H Balsley, J Roark… - FEMS microbiology …, 2006 - academic.oup.com
Many human diseases are caused by pathogens that produce exotoxins. The genes that
encode these exotoxins are frequently encoded by mobile DNA elements such as plasmids …

Cloning of a gene involved in regulation of exotoxin A expression in Pseudomonas aeruginosa

RC Hedstrom, CR Funk, JB Kaper… - Infection and …, 1986 - Am Soc Microbiol
We have cloned a gene from Pseudomonas aeruginosa that stimulates the expression of
exotoxin A. A recombinant library of genomic DNA from strain PA103 constructed with a …

Isolation and characterization of a Pseudomonas aeruginosa gene, ptxR, which positively regulates exotoxin A production

AN Hamood, JA Colmer, UA Ochsner… - Molecular …, 1996 - Wiley Online Library
Exotoxin A production in Pseudomonas aeruginosa is a complicated and highly regulated
process that involves several genes. In this report, we describe the isolation of a new toxA …

Bacterial exotoxins

MR Popoff - Contributions to microbiology, 2005 - books.google.com
Amongst the various mechanisms developed by pathogenic bacteria to cause disease,
toxins play an important role, since they are responsible for the majority of symptoms and …

Possible insertion sequences in a mosaic genome organization upstream of the exotoxin A gene in Pseudomonas aeruginosa

AE Pritchard, ML Vasil - Journal of bacteriology, 1990 - Am Soc Microbiol
Nucleotide sequence and Southern hybridization data revealed a mosaic genome
organization in a region that extends several thousand base pairs upstream of the exotoxin …

[HTML][HTML] Cloning and expression of the immunogenic moiety of Pseudomonas aeruginosa exotoxin A

S Nouri Gharajelar, M Ahmadi, B Hosseini - Biological Journal of …, 2013 - bjm.ui.ac.ir
Introduction: Pseudomonas aeruginosa, as an opportunistic microorganism, is a major
cause of nosocomial infections worldwide. Exotoxin A (ETA) is an extracellular enzyme that …

Molecular studies of Pseudomonas exotoxin A gene

ML Vasil, C Chamberlain, CC Grant - Infection and immunity, 1986 - Am Soc Microbiol
A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was
divided into three nonoverlapping probes. Two probes covering the ETA structural gene …

A ToxIN homolog from Salmonella enterica serotype Enteritidis impairs bacteriophage infection

JA McFarlane, EG Hansen, EC Ortega… - Journal of Applied …, 2023 - academic.oup.com
Aims To determine if the bacteriophage abortive infection system ToxIN is present in
foodborne Salmonella and if it protects against infection by bacteriophages specific to …