Exploring disease through metabolomics
N Vinayavekhin, EA Homan… - ACS chemical biology, 2010 - ACS Publications
Metabolomics approaches provide an analysis of changing metabolite levels in biological
samples. In the past decade, technical advances have spurred the application of …
samples. In the past decade, technical advances have spurred the application of …
Metabolomics: beyond biomarkers and towards mechanisms
Metabolomics, which is the profiling of metabolites in biofluids, cells and tissues, is routinely
applied as a tool for biomarker discovery. Owing to innovative developments in informatics …
applied as a tool for biomarker discovery. Owing to innovative developments in informatics …
Identification of bioactive metabolites using activity metabolomics
The metabolome, the collection of small-molecule chemical entities involved in metabolism,
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
Metabolomics toward personalized medicine
M Jacob, AL Lopata, M Dasouki… - Mass spectrometry …, 2019 - Wiley Online Library
Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …
biomarker discovery and personalized medicine and has great potential to elucidate the …
Metabolomics: an emerging but powerful tool for precision medicine
CB Clish - Molecular Case Studies, 2015 - molecularcasestudies.cshlp.org
Metabolomics, which is defined as the comprehensive analysis of metabolites in a biological
specimen, is an emerging technology that holds promise to inform the practice of precision …
specimen, is an emerging technology that holds promise to inform the practice of precision …
Cell metabolomics
A Zhang, H Sun, H Xu, S Qiu, X Wang - Omics: a journal of …, 2013 - liebertpub.com
Metabolomics technologies enable the examination and identification of endogenous
biochemical reaction products, revealing information on the precise metabolic pathways and …
biochemical reaction products, revealing information on the precise metabolic pathways and …
Modern analytical techniques in metabolomics analysis
A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …
systematically identify and quantify metabolites from a biological sample. Small-molecule …
Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine
A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
The potential of metabolomics in biomedical applications
V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …