Metabolomics as a truly translational tool for precision medicine

JC Schmidt, BV Dougherty, RD Beger… - … journal of toxicology, 2021 - journals.sagepub.com
Metabolomics is unique among omics technologies in being applicable to metabolism and
toxicity studies broadly across organisms (eg, humans, other mammals, model organisms …

[HTML][HTML] Metabolomics in toxicology and preclinical research

T Ramirez, M Daneshian, H Kamp, FY Bois, MR Clench… - Altex, 2013 - ncbi.nlm.nih.gov
Metabolomics, the comprehensive analysis of metabolites in a biological system, provides
detailed information about the biochemical/physiological status of a biological system, and …

Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

[图书][B] The handbook of metabolomics

TWM Fan, AN Lane, RM Higashi - 2012 - Springer
Metabolomics is a rapidly expanding field that provides a link between functional biology
(phenotypes) and the inner workings of cells in tissues or whole organisms. The …

Toward the implementation of metabolomic assessments of human health and nutrition

SM Watkins, JB German - Current Opinion in Biotechnology, 2002 - Elsevier
Metabolomics is emerging as an exciting post-genomic science with applications that span
the scope of biotechnology and medicine. Although metabolomics is still in its infancy, it has …

Metabolomics in toxicology: preclinical and clinical applications

DG Robertson, PB Watkins, MD Reily - Toxicological sciences, 2011 - academic.oup.com
Metabolomics first burst into the toxicology arena approximately 10–12 years ago,
experiencing rapid growth as a science in the intervening period (Fig. 1). Though …

Introduction to metabolomics

J Adamski - Metabolomics for Biomedical Research, 2020 - Elsevier
Metabolomics addresses a comprehensive view of metabolites depicting biological and
nonenzymatic processes. The metabolomics requests integrative application of …

Exploring disease through metabolomics

N Vinayavekhin, EA Homan… - ACS chemical biology, 2010 - ACS Publications
Metabolomics approaches provide an analysis of changing metabolite levels in biological
samples. In the past decade, technical advances have spurred the application of …

Metabolomics toward personalized medicine

M Jacob, AL Lopata, M Dasouki… - Mass spectrometry …, 2019 - Wiley Online Library
Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …

The potential of metabolomics in biomedical applications

V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …