Polyamidoamine dendrimer-polyethylene glycol hydrogel for solubility enhancement and sustained release of diflunisal

Z Kegley, M Makay, J Rogers, K Phelps… - Journal of Sol-Gel …, 2022 - Springer
The purpose of this research is to develop a hydrogel delivery system for solubility
enhancement and sustained release of hydrophobic drugs. The model drug, diflunisal, has …

Polyamidoamine dendrimer-mediated hydrogel for solubility enhancement and anti-cancer drug delivery

X Bi, DB Watts, I Dorman, CM Kirk… - Journal of …, 2024 - journals.sagepub.com
The application of hydrogels for anti-cancer drug delivery has garnered considerable
interest in the medical field. Current cancer treatment approaches, such as chemotherapy …

PAMAM dendrimer hydrogel film—Biocompatible material to an efficient dermal delivery of drugs

TM Magalhães, RC Guerra, RAS San Gil… - Journal of Nanoparticle …, 2017 - Springer
We report the preparation, characterization, and drug release kinetics of a pH-responsive
hydrogel film from a dendrimer megamer. The megamer (GP32) is a three-dimensional …

Preparation and characterization of novel physically cross‐linked hydrogels composed of poly (vinyl alcohol) and amine‐terminated polyamidoamine dendrimer

XY Wu, SW Huang, JT Zhang… - Macromolecular …, 2004 - Wiley Online Library
Poly (vinyl alcohol)(PVA) and polyamidoamine (PAMAM) dendrimers are water‐soluble,
biocompatible and biodegradable polymers, which have been widely applied in biomedical …

Dendrimer-based hydrogels with controlled drug delivery property for tissue adhesion

YQ Wang, XY Dou, HF Wang, X Wang… - Chinese Journal of …, 2021 - Springer
In recent years, the hydrogel-based tissue adhesives have been extensively investigated for
their excellent biocompatibility and the ability to be administered directly within the adherent …

Dendrimer for solubility enhancement

B Gorain, M Pandey, H Choudhury, GK Jain… - Dendrimer-based …, 2021 - Elsevier
A drug is effective in their molecular form; thus solubility in the biological fluid is important.
Pharmaceutical researchers are continuously working on the improvement of solubility of …

Mussel-inspired controllable drug release hydrogel for transdermal drug delivery: Hydrogen bond and ion-dipole interactions

Y Cai, L Xin, H Li, P Sun, C Liu, L Fang - Journal of Controlled Release, 2024 - Elsevier
Hydrogels have broad application prospects in drug delivery due to their biocompatibility,
high water content and three-dimensional structure. However, the regulation of drug release …

A Supramolecular Hydrogel Based on Polyglycerol Dendrimer‐Specific Amino Group Recognition

IS Cho, T Ooya - Chemistry–An Asian Journal, 2018 - Wiley Online Library
Dendrimer‐based supramolecular hydrogels have gained attention in biomedical fields.
While biocompatible dendrimers were used to prepare hydrogels via physical and/or …

Co-delivery of doxorubicin and curcumin by a pH-sensitive, injectable, and in situ hydrogel composed of chitosan, graphene, and cellulose nanowhisker

S Omidi, M Pirhayati, A Kakanejadifard - Carbohydrate polymers, 2020 - Elsevier
Hydrogels are promising carriers for the controlled drug delivery in response to the external
stimuli such as pH and temperature. Here, a new hydrogel is designed and synthesized from …

Synthesis and characterization of a hydrophobic association hydrogel for drug delivery

HHC de Lima, GM Santos, CTP da Silva… - Journal of Molecular …, 2023 - Elsevier
This work reports the synthesis, characterization, and evaluation of a hydrophobic
association hydrogel containing vinyl alginate (SA), acrylamide, and the hydrophobic …