Glycosyltransferase-catalyzed enzymatic and chemoenzymatic syntheses are powerful
approaches for the production of oligosaccharides, polysaccharides, glycoconjugates, and …

Glycosynthases are hydrolytically incompetent engineered glycosidases that catalyze the
high-yielding synthesis of glycoconjugates from glycosyl fluoride donor substrates and …

Enzymes continue to be used as important catalysts, for the generation of rare and
'unnatural'monosaccharides and for the selective formation of glycosidic linkages. Multi …

Oligosaccharides, in either free or bound forms, play crucial roles in a wide range of
biological processes. Increasing appreciation of their roles in cellular communication …

Carbohydrate mimetics that are resistant towards enzymatic hydrolysis have proven to be
useful as competitive glycosidase inhibitors and therefore have potential as therapeutics …

A robust platform for facile defined glycan synthesis does not exist. Yet the need for such
technology has never been greater as researchers seek to understand the full scope of …

Background: Retaining glycosidases can catalyse glycosidic bond formation through
transglycosylation from a donor sugar to an acceptor bound in the aglycone site. The …

Although glycoscientists have learned over the years how to isolate certain classes of
naturally occurring complex carbohydrates, the availability of pure natural isolates, remains …

Carbohydrates are attached and removed in living systems through the action of
carbohydrate‐active enzymes such as glycosyl transferases and glycoside hydrolases. The …

The development of efficient, fast, flexible and general synthetic routes to glycopolymers is
an ongoing challenge and much progress has been made in recent years. Chemical …