Enzymes in organic synthesis: application to the problems of carbohydrate recognition (part 1)

CH Wong, RL Halcomb, Y Ichikawa… - … International Edition in …, 1995 - Wiley Online Library
Carbohydrates on cell surfaces are information molecules. Although only seven or eight
monosaccharides are commonly used as building blocks in mammalian systems, the …

[HTML][HTML] β-Glycosyl azides as substrates for α-glycosynthases: Preparation of efficient α-L-fucosynthases

B Cobucci-Ponzano, F Conte, E Bedini, MM Corsaro… - Chemistry & biology, 2009 - cell.com
Fucose-containing oligosaccharides play a central role in physio-pathological events, and
fucosylated oligosaccharides have interesting potential applications in biomedicine. No …

Recent progress in chemical and chemoenzymatic synthesis of carbohydrates

S Muthana, H Cao, X Chen - Current opinion in chemical biology, 2009 - Elsevier
The important roles that carbohydrates play in biological processes and their potential
application in diagnosis, therapeutics, and vaccine development have made them attractive …

[引用][C] Spacer-modified oligosaccharides as potential affinity reagents for glycosyltransferases: the preparation and enzymic galactosylation of 1, 10-bis (2-acetamido …

J Lehmann, S Petry - Carbohydrate research, 1990 - Elsevier
Many glycoconjugates of eukaryotic cells, glycolipids, and glycoproteins have specific and
important biological functions'. In order to fulfil these functions, the assembly of the …

Protecting groups as a factor of stereocontrol in glycosylation reactions

AI Tokatly, DZ Vinnitskiy, NE Ustuzhanina… - Russian Journal of …, 2021 - Springer
Synthetic oligosaccharides are objects of interest as model compounds in studies on the
biological activity of natural compounds, but also as components for new drugs …

Glycosyltransferases in the synthesis of oligosaccharide analogs

MM Palcic, O Hindsgaul - Trends in Glycoscience and …, 1996 - jstage.jst.go.jp
抄録 この総説では糖転移酵素によるオリゴ糖類似体の合成について概観する. 特に,
化学修飾された糖ヌクレオチド供与体, あるいは化学修飾された糖受容体を基質として用いたものに …

Site-selective modification of (oligo) saccharides

MD Witte, AJ Minnaard - ACS catalysis, 2022 - ACS Publications
Oligosaccharides, either as such or as part of glycolipids, glycopeptides, or glycoproteins,
are ubiquitous in nature and fulfill important roles in the living cell. Also in medicine and to …

Enzymatic synthesis of oligosaccharides by two glycosyl hydrolases of Sulfolobus solfataricus

M Moracci, A Trincone, B Cobucci-Ponzano… - Extremophiles, 2001 - Springer
The importance of carbohydrates in a variety of biological functions is the reason that
interest has recently increased in these compounds as possible components of therapeutic …

Recent developments in stereoselective chemical glycosylation

J Ling, CS Bennett - Asian journal of organic chemistry, 2019 - Wiley Online Library
Because of their pivotal biological functions, attention to sugars and glycobiology has grown
rapidly in recent decades, leading to increased demand for homogeneous oligosaccharides …

Large-scale production of oligosaccharides using bacterial functions

S Koizumi - Trends in Glycoscience and Glycotechnology, 2003 - jstage.jst.go.jp
Oligosaccharides on the cell surface that play important roles in the biochemical recognition
processes are potential pharmaceuticals. However it has been very difficult to synthesize …