This study was performed to examine the immunologic basis for the apparent ethnic
difference in clinical outcome of hepatitis C virus (HCV) infection between African Americans …

Many T cells infiltrate into the liver of patients with chronic hepatitis C (CH-C). They are
believed to play a crucial role in the immunopathogenesis of hepatic inflammation, but their …

Purpose. An imbalance in helper T-cell type 1 (Th1) and type 2 (Th2) cytokines is suggested
to play an important role in the pathogenesis of chronic viral infections, but this issue is not …

An imbalance between T helper cell (Th) 1 and Th2–like cytokines has been described in
several chronic infectious diseases. We therefore analyzed the intrahepatic messenger RNA …

Cellular immune responses are likely to play a key role in determining the clinical outcome
in acute infection with hepatitis C virus (HCV), but the dynamics of such responses and their …

ESOLUTION of acute hepatitis C is generally associ-R ated with detection of neutralizing
antibodies, a high frequency of circulating HCV-specific T cells with a predominant …

Aim: To evaluate the immune response in peripheral blood and liver tissue, through the
measurement of T-cell subsets, in patients with chronic hepatitis B (CHB) and C (CHC) …

Abstract Virus‐specific CD8+ T‐cells play an important role in the outcome of acute hepatitis
C virus (HCV) infection. In the chronic phase, however, HCV can persist despite the …

CD4+ T‐cell responses are important for the outcome of hepatitis C virus (HCV) infection.
However, the functional status of HCV‐specific CD4+ T cells in persistent infection is poorly …

T cells are believed to be the main players in antiviral defence. To investigate the role of the
specific CD4+ T cell response for clearance and control of the hepatitis C virus we studied …