The efficacy of antioxidants administered during low temperature storage of warm ischemic kidney tissue slices

JF McAnulty, XQ Huang - Cryobiology, 1997 - Elsevier
Accumulation of products of lipid peroxidation (malondialdehyde, conjugated dienes, lipid
peroxides, and Schiff bases) was evaluated in rabbit kidney cortex slices made ischemic for …

The beneficial effect of intermediate normothermic perfusión during cold storage of ischemically injured kidneys

JG Maessen, GERJ VAN DER VUSSE, M VORK… - …, 1989 - journals.lww.com
The effect of simple cold storage on ice with or without preceding warm ischemic injury on
the energy metabolism and posttransplant viability of canine kidneys was examined in the …

Dose‐Ranging Study of the Performance of the Natural Oxygen Transporter HEMO2Life in Organ Preservation

V Mallet, D Dutheil, V Polard, M Rousselot… - Artificial …, 2014 - Wiley Online Library
The intensity of ischemia–reperfusion injury of the donor organ during the preservation
phase and after anastomosis is acknowledged as being a key factor for long‐term graft …

Hypothermic pulsatile perfusion of dog kidneys: factors limiting successful preservation time

R Grundman, T Landes, H Pichlmaier - Transplantation, 1972 - journals.lww.com
Dog kidneys under hypothermia were perfused with canine plasma for up to 72 hr and
thereafter autotransplanted. Oxygen tensions, pH, temperature, and osmolarity of the …

Benefits of active oxygenation during hypothermic machine perfusion of kidneys in a preclinical model of deceased after cardiac death donors

R Thuillier, G Allain, O Celhay, W Hebrard… - Journal of Surgical …, 2013 - Elsevier
Background Deceased after cardiac death donors (DCDs) represent a valuable source of
organs; however, preventing poor outcome is difficult, even with the use of machine …

Oxygenated machine perfusion preservation of predamaged kidneys with HTK and Belzer machine perfusion solution: An experimental study in pigs

S Manekeller, H Leuvenink, M Sitzia, T Minor - Transplantation …, 2005 - Elsevier
The objective of the present study was to evaluate the recently proposed aerobic machine
preservation with the noncolloidal HTK solution by comparison with the colloidal Belzer …

Kidney preservation ex vivo for transplantation

JV Bonventre, JM Weinberg - Annual review of medicine, 1992 - annualreviews.org
Ischemic injury to the renal allograft, prior to implantation, is an important cause of delayed
graft function. With improved understanding of the pathophysiological mechanisms involved …

Solution for the preservation of organs

FD Belzer, JH Southard - US Patent 4,879,283, 1989 - Google Patents
BACKGROUND OF THE INVENTION Renal preservation, the ex vivo storage of cadaveric
kidneys, is a relatively new? eld. Preservation of cadav eric kidneys for transplantation is …

In vitro preservation of whole organs by hypothermia and hyperbaric oxygenation

RC Lillehei, WG Manax, JH Bloch, Z Eyal, F Hidalgo… - Cryobiology, 1964 - Elsevier
Canine whole organs (kidney, heart, small bowel) have been successfully preserved for 48
hours in an in vitro viable state by the combination of hypothermia (2° to 4° C) and …

[HTML][HTML] Hypothermia–a limiting factor in using warm ischemically damaged kidneys

L Brasile, BM Stubenitsky, MH Booster… - American journal of …, 2001 - Elsevier
A study was performed to determine the limiting factors to expanding the donor pool with
warm ischemically (WI) damaged kidneys. Canine kidneys were damaged by 30 min of WI …