The pathogenic, diagnostic and therapeutic landscape of sepsis is no longer confined to the
intensive care unit: many patients from other portals of entry to care, both outside and within …

Despite numerous advances in medicine, sepsis remains an unconquered challenge.
Although outcomes have improved slightly over decades, the unacceptably high mortality …

Severe sepsis and septic shock are as common and lethal as other acute life-threatening
conditions that emergency physicians routinely confront such as acute myocardial infarction …

Significant advances have been made in our understanding of the septic cascade and our
ability to manage patients with severe sepsis and septic shock. Despite these advances …

There has been a significant evolution in the definition and management of sepsis over the
last three decades. This is driven in part due to the advances made in our understanding of …

The diagnosis and management of severe sepsis and septic shock is a complex and
dynamic process. Newer evidence-based interventions are constantly being developed and …

Early management of sepsis and septic shock is crucial for patients' prognosis. As the
Emergency Department (ED) is the place where the first medical contact for septic patients is …

Sepsis is among the most common reasons for admission to ICUs throughout the world, and
it is believed to be the third most common cause of death in the United States. The …

Sepsis and related aspects has become an area of active and intense research, leading to
important advances for an early diagnosis and appropriate management useful to improve …

The complexity of treating severe sepsis and septic shock has been elucidated in myriad
studies, particularly in the past 10 years. The development of clinical guidelines, insight into …