High-throughput sorting of eggs for synchronization of C. elegans in a microfluidic spiral chip

S Sofela, S Sahloul, M Rafeie, T Kwon, J Han… - Lab on a Chip, 2018 - pubs.rsc.org
In this study, we report the use of a high-throughput microfluidic spiral chip to screen out
eggs from a mixed age nematode population, which can subsequently be cultured to a …

Versatile size-dependent sorting of C. elegans nematodes and embryos using a tunable microfluidic filter structure

L Dong, M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2016 - pubs.rsc.org
The roundworm Caenorhabditis elegans (C. elegans) is a powerful model organism for
addressing fundamental biological questions related to human disease and aging. Its life …

PDMS filter structures for size-dependent larval sorting and on-chip egg extraction of C. elegans

HB Atakan, F Ayhan, MAM Gijs - Lab on a Chip, 2020 - pubs.rsc.org
C. elegans-based assays require age-synchronized populations prior to experimentation to
achieve standardized sets of worm populations, due to which age-induced heterogeneous …

Microfluidic-Assisted Caenorhabditis elegans Sorting: Current Status and Future Prospects

H Yuan, W Yuan, S Duan, K Jiao, Q Zhang… - Cyborg and Bionic …, 2023 - spj.science.org
Caenorhabditis elegans (C. elegans) has been a popular model organism for several
decades since its first discovery of the huge research potential for modeling human diseases …

[HTML][HTML] An Automated Microfluidic Multiplexer for Fast Delivery of C. elegans Populations from Multiwells

N Ghorashian, SK Gökçe, SX Guo, WN Everett… - PloS one, 2013 - journals.plos.org
Automated biosorter platforms, including recently developed microfluidic devices, enable
and accelerate high-throughput and/or high-resolution bioassays on small animal models …

A microfluidic diode for sorting and immobilization of Caenorhabditis elegans

L Yang, T Hong, Y Zhang, JGS Arriola, BL Nelms… - Biomedical …, 2017 - Springer
Caenorhabditis elegans (C. elegans) is a powerful model organism extensively used in
studies of human aging and diseases. Despite the numerous advantages of C. elegans as a …

An Automated Microfluidic System for Morphological Measurement and Size-Based Sorting of C. Elegans

X Dong, P Song, X Liu - IEEE Transactions on Nanobioscience, 2019 - ieeexplore.ieee.org
This paper reports a vision-based automated microfluidic system for morphological
measurement and size-based sorting of the nematode worm C. elegans. Exceeding the …

A high-throughput device for size based separation of C. elegans developmental stages

X Ai, W Zhuo, Q Liang, PT McGrath, H Lu - Lab on a Chip, 2014 - pubs.rsc.org
Caenorhabditis elegans is a widely used model organism to study development, aging and
behavior. Many of these biological studies require staging a large number of worms to assay …

[HTML][HTML] Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

HB Atakan, R Xiang, M Cornaglia, L Mouchiroud… - Scientific reports, 2019 - nature.com
The nematode Caenorhabditis elegans is a suitable model organism in drug screening.
Traditionally worms are grown on agar plates, posing many challenges for long-term culture …

[HTML][HTML] Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans

BP Gupta, P Rezai - Micromachines, 2016 - mdpi.com
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies
related to fundamental biological processes, disease modelling, and drug discovery. Due to …