Determination of pipecolic acid in urine and plasma by isotope dilution mass fragmentography

GA van den Berg, H Breukelman, H Elzinga… - Clinica Chimica …, 1986 - Elsevier
A capillary gas Chromatographie method with mass spectrometric detection for the
determination of pipecolic acid in urine and plasma (or serum) has been developed. Using a …

Stable isotope dilution analysis of pipecolic acid in cerebrospinal fluid, plasma, urine and amniotic fluid using electron capture negative ion mass fragmentography

RM Kok, L Kaster, APJM de Jong, B Poll-Thé… - Clinica chimica acta, 1987 - Elsevier
A sensitive and accurate stable isotope dilution assay was developed for the measurement
of pipecolic acid in body fluids using electron capture negative ion mass fragmentography …

The determination of pipecolic acid: method and results of hospital survey

J Hutzler, J Dancis - Clinica Chimica Acta, 1983 - Elsevier
A method is described for the quantitative assay of pipecolic acid in biological fluids using
column chromatography, with acid ninhydrin for color development. The technique permits …

[引用][C] Determination of pipecolic acid in human blood plasma by high-performance liquid chromatography

N Hiroaki, S Tomio - Clinica chimica acta, 1984 - Elsevier
The description of severe metabolic disorders of the central nervous system, such as
hyperlysinemia[l], Zellweger's disease [2, 3] and hyperpipecolatemia[4, 5], which are related …

Analysis of pipecolic acid in biological fluids using capillary gas chromatography with electron-capture detection and [2H11] pipecolic acid as internal standard

T Zee, F Stellaard, C Jakobs - Journal of Chromatography B: Biomedical …, 1992 - Elsevier
A sensitive and accurate stable isotope dilution assay was developed for the measurement
of pipecolic acid in body fluids using capillary gas chromatography with electron-capture …

Excretion of pipecolic acid by infants and by patients with hyperlysinemia

NC Woody, MB Pupene - Pediatric Research, 1970 - nature.com
Extract: Pipecolic acid has been found in urine from normal infants and from children with
hyperlysinemia. The reaction of pipecolic acid with ninhydrin reagent, using separation …

The determination of pipecolic acid in serum and urine

RF Grimble - Clinica Chimica Acta, 1972 - Elsevier
A method is described for the determination of the imino acid, pipecolic acid in serum and
urine. Serum is deproteinised with absolute ethanol and urine is desalted by ion exchange …

Sensitive determination of pipecolic acid in serum by high-performance liquid chromatography using 4-(5, 6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfonyl …

H Inoue, Y Sakata, K Fukunaga, H Nishio… - Analytica chimica …, 2004 - Elsevier
A simple and highly sensitive high-performance liquid chromatography (HPLC) for the
determination of pipecolic acid (PA) in serum was developed. Pipecolic acid and nipecotic …

Origin of D-and L-pipecolic acid in human physiological fluids: a study of the catabolic mechanism to pipecolic acid using the lysine loading test

T Fujita, T Hada, K Higashino - Clinica chimica acta, 1999 - Elsevier
Pipecolic acid, a metabolite of lysine, is found in human physiological fluids. It is known that
plasma pipecolic acid levels are elevated in patients with Zellweger syndrome, a genetic …

Pipecolic acid levels in serum and urine from neonates and normal infants: comparison with values reported in Zellweger syndrome

L Govaerts, F Trijbels, L Monnens… - Journal of inherited …, 1985 - Springer
Pipecolic acid (PA) excretion from normal newborn, preterm and/or small-for-dates infants
has been determined and correlated with gestational age, sex and age after birth. An effect …