BACKGROUND: The Inhaled Steroid Treatment as Regular Therapy in Early Asthma
(START) study is a worldwide, randomized, prospective study to investigate early …

Asthma is a leading cause of morbidity in children, leading to frequent emergency room
visits and hospitalizations. In recent years, a steady increase in the number of cases of …

The effects of inhaled corticosteroids (ICSs) in asthma include reduced severity of
symptoms, improved pulmonary function, diminished bronchial hyperresponsiveness (BHR) …

Although twice-daily administration of ICS is often better to optimize asthma parameters, in
many patients, asthma can be sufficiently controlled by a once-daily regimen of most ICS. An …

This narrative review provides evidence-based explanations to some of the common clinical
concerns regarding inhaled corticosteroids. Inhaled corticosteroids are the treatment of …

The National Asthma Education and Prevention Program 1997 guidelines and 2002 update
provide an overview of potential local and systemic side effects associated with inhaled …

Purpose To study persistence with inhaled corticosteroids (ICS) and its determinants in
asthma‐patients. Methods From the PHARMO database, asthma‐patients (age< 35 years) …

The systemic activity and safety of inhaled corticosteroids are best studied in randomized,
controlled, long-term trials with clinically relevant doses in subjects. These studies require …

The review illustrates the complexity of treating wheezing in infants and preschoolers and
interpreting the study results. It emphasizes the need for more studies in clinical subgroups …

If started early and at high doses, the acute use of inhaled corticosteroids (ICS) provides
modest benefit in patients with mild exacerbations of asthma. In more severe exacerbations …