Genetic variability and haplotype profile of MDR1 in Saudi Arabian males
AM Al-Mohizea, KM Alkharfy, KM Bagulb… - Molecular biology …, 2012 - Springer
Polymorphisms in multidrug resistance (MDR1) gene play an important role in influencing
the pharmacological action and toxicity profile of a large number of therapeutic agents, and …
the pharmacological action and toxicity profile of a large number of therapeutic agents, and …
[HTML][HTML] Simultaneous analysis of multidrug resistance 1 (MDR1) C3435T, G2677T/A, and C1236T genotypes in Hamadan City population, West of Iran
M Saidijam, H Mahjub, N Shabab… - Iranian Biomedical …, 2015 - ncbi.nlm.nih.gov
Background: One of the limitations in the treatment of common diseases such as cancer
chemotherapy is development of multidrug resistance (MDR). Polymorphisms could alter the …
chemotherapy is development of multidrug resistance (MDR). Polymorphisms could alter the …
[PDF][PDF] Frequency of MDR1 single nucleotide polymorphisms in a Jordanian population, including a novel variant
The multidrug resistance gene (MDR1 or ABCB1) codes for P-glycoprotein, which plays an
important role in regulating absorption, distribution, and elimination of drugs. We examined …
important role in regulating absorption, distribution, and elimination of drugs. We examined …
Genotype Variability and Haplotype Frequency of MDR1 (ABCB1) Gene Polymorphism in Morocco
Y Kassogue, H Dehbi, S Nassereddine… - DNA and cell …, 2013 - liebertpub.com
The multidrug resistance gene (MDR1) plays an important role in the transport of a wide
range of drugs and elimination of xenobiotics from the body. Identification of polymorphisms …
range of drugs and elimination of xenobiotics from the body. Identification of polymorphisms …
[PDF][PDF] Genotype and allele frequencies of MDR-1 gene polymorphism in Jordanian and Sudanese populations
AH Salem, M Ali, A Ibrahim, M Ibrahim - Am J Med Stud, 2014 - researchgate.net
The aim of this study was to determine the genotype and allele frequencies of MDR1 gene
C3435T polymorphism in Jordanian and Sudanese populations, and to compare them with …
C3435T polymorphism in Jordanian and Sudanese populations, and to compare them with …
Genomic evidence for recent positive selection at the human MDR1 gene locus
K Tang, LP Wong, EJD Lee, SS Chong… - Human molecular …, 2004 - academic.oup.com
The MDR1 multidrug transporter regulates the traffic of drugs, peptides and xenobiotics into
the body as well as sensitive tissues like the brain, germ cells and the developing fetus …
the body as well as sensitive tissues like the brain, germ cells and the developing fetus …
The single nucleotide polymorphism and haplotype analysis of MDR1 in Jiangsu Han population of China
H Qiu, H Dong, S Pan, K Miao - Biomedicine & Pharmacotherapy, 2012 - Elsevier
The aim of this study was to perform the frequency distribution of MDR1 gene SNPs and
haplotypes of Jiangsu Han population in China. A total of 225 Jiangsu Han unrelated …
haplotypes of Jiangsu Han population in China. A total of 225 Jiangsu Han unrelated …
Frequency of the C1236T, G2677T/A and C3435T MDR1 gene polymorphisms in the Serbian population
M Milojkovic, S Stojnev, I Jovanovic… - Pharmacological …, 2011 - Springer
The multi-drug resistance 1 (MDR1) gene encodes for a P-glycoprotein (PGP), which acts as
a gate-keeper against various kinds of xenobiotics. Several single nucleotide …
a gate-keeper against various kinds of xenobiotics. Several single nucleotide …
Distribution of the single nucleotide polymorphism C3435T of MDR1 gene among people in Western Australia, Australia
What is known: Ethnic variation as well as the population frequency of the MDR1 C3435T
transition has been observed in the few other populations but not in Australians. Objective …
transition has been observed in the few other populations but not in Australians. Objective …
Genotype and allele frequency of human multidrug resistance (MDR1) gene C3435T polymorphism in Denizli province of Turkey
Human p-glycoprotein encoded by human multidrug resistance (MDR1) gene, is a
transmembrane protein that serves as efflux pump for a wide variety of lipophilic compounds …
transmembrane protein that serves as efflux pump for a wide variety of lipophilic compounds …