Low sensitivity in clinical diagnoses of dementia with Lewy bodies

PT Nelson, GA Jicha, RJ Kryscio, EL Abner… - Journal of …, 2010 - Springer
The success of future neurodegenerative disease (ND) therapies depends partly on
accurate antemortem diagnoses. Relatively few prior studies have been performed on large …

What best differentiates Lewy body from Alzheimer's disease in early-stage dementia?

P Tiraboschi, DP Salmon, LA Hansen, RC Hofstetter… - Brain, 2006 - academic.oup.com
To determine which clinical feature (s)[among visual hallucinations (VH), extrapyramidal
signs (EPS) and visuospatial impairment] in the earliest stages of disease best predicted a …

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) Report of the consortium on DLB international workshop

IG McKeith, D Galasko, K Kosaka, EK Perry… - Neurology, 1996 - AAN Enterprises
Recent neuropathologic autopsy studies found that 15 to 25% of elderly demented patients
have Lewy bodies (LB) in their brainstem and cortex, and in hospital series this may …

Diagnostic accuracy of dementia with Lewy bodies

U Hohl, P Tiraboschi, LA Hansen, LJ Thal… - Archives of …, 2000 - jamanetwork.com
Background Diagnostic criteria for dementia with Lewy bodies (DLB) are still evolving. No
data exist on prospective differentiation of DLB and Alzheimer disease (AD). Objective To …

Improving the identification of dementia with Lewy bodies in the context of an Alzheimer's-type dementia

AJ Thomas, F Mahin-Babaei, M Saidi, D Lett… - Alzheimer's research & …, 2018 - Springer
Abstract Background Dementia due to Alzheimer's disease (AD) and dementia with Lewy
bodies (DLB) are the two most common neurodegenerative causes of dementia. They …

Cognitive loss in dementia with Lewy bodies and Alzheimer disease

T Shimomura, E Mori, H Yamashita… - Archives of …, 1998 - jamanetwork.com
Background Dementia with Lewy bodies (DLB) is emerging as a common cause of
degenerative dementia. Some preliminary evidence exists that the pattern of cognitive …

Clinicopathologic correlates in temporal cortex in dementia with Lewy bodies

T Gomez-Isla, WB Growdon, M McNamara, K Newell… - Neurology, 1999 - AAN Enterprises
Objective: To address the relationship between dementia and neuropathologic findings in
dementia with Lewy bodies (DLB) in comparison with AD. Methods: We evaluated the …

Validity of clinical criteria for the diagnosis of dementia with Lewy bodies

J Verghese, HA Crystal, DW Dickson, RB Lipton - Neurology, 1999 - AAN Enterprises
Objective: To assess the clinical validity of clinical diagnostic criteria for dementia with Lewy
bodies (DLB). Methods: We assessed the sensitivity, specificity, and positive and negative …

Dementia with Lewy bodies versus Alzheimer's disease and Parkinson's disease dementia: a comparison of cognitive profiles

KW Park, HS Kim, SM Cheon, JK Cha… - Journal of clinical …, 2011 - synapse.koreamed.org
Background and Purpose It is particularly difficult to differentiate dementia with Lewy bodies
(DLB) from the related dementias of Alzheimer's disease (AD) and Parkinson's disease …

Research evaluation and prospective diagnosis of dementia with Lewy bodies

OL Lopez, JT Becker, DI Kaufer, RL Hamilton… - Archives of …, 2002 - jamanetwork.com
Objective To evaluate the relative merits of recently developed criteria for dementia with
Lewy bodies (DLBs) in a longitudinal study of dementia. Design The diagnosis of DLBs was …