Some recent studies showed that the glucocorticoid-induced muscle atrophy was associated
with myostatin, a negative regulator of skeletal muscle. In this study, two experiments were …

Glucocorticoids mediate muscle atrophy in many catabolic states. Myostatin expression, a
negative regulator of muscle growth, is increased by glucocorticoids and myostatin …

The mechanisms by which excessive glucocorticoids cause muscular atrophy remain
unclear. We previously demonstrated that dexamethasone increases the expression of …

Excess glucocorticoids (GCs) cause muscle atrophy. Glucocorticoid-induced muscle atrophy
is associated with increased intramuscular myostatin expression. Myostatin is a negative …

We cloned and characterized a 3.3-kb fragment containing the 5′-regulatory region of the
human myostatin gene. The promoter sequence contains putative muscle growth response …

Myostatin is a specific negative regulator of skeletal muscle growth and is regarded as one
of the most important factors for myogenesis. The aim of the current study was to analyze the …

Myostatin is a master regulator of myogenesis and early postnatal skeletal muscle growth.
However, myostatin has been also involved in several forms of muscle wasting in adulthood …

Compared with the understanding for the functional mechanism of the myostatin gene, little
is known about the regulatory mechanism of the myostatin gene transcription and …

Myostatin is a recently discovered member of transforming growth factor beta (TGFbeta)
superfamily and shares similar structure features with other members of TGFbeta …

Myostatin is a negative regulator of muscle growth, and absence of the functional myostatin
protein leads to the heavy muscle phenotype in both mouse and cattle. Although the role of …