The different cell types in the brain have highly specialized roles with unique metabolic
requirements. Normal brain function requires the coordinated partitioning of metabolic …

Malignant gliomas are intractable and among the most lethal human malignancies. Like
other cancers, metabolic reprogramming is a key feature of glioma and is thought to …

During metabolic reprogramming, glioma cells and their initiating cells efficiently utilized
carbohydrates, lipids and amino acids in the hypoxic lesions, which not only ensured …

Glioblastoma is a primary malignant brain tumor with a median survival under 2 years. The
poor prognosis glioblastoma caries is largely due to cellular invasion, which enables escape …

The fields of tumor metabolism and immune oncology have both independently received
considerable attention over the last several years. The majority of research in tumor …

The metabolism of glioblastoma (GBM), the most aggressive and lethal primary brain tumor,
is flexible and adaptable to different adverse conditions, such as nutrient deprivation …

The metabolic complexity and flexibility commonly observed in brain tumors, especially
glioblastoma, is fundamental for their development and progression. The ability of tumor …

Glioblastoma (GBM) is one of the most aggressive tumors. Numerous studies in the field of
immunotherapy have focused their efforts on identifying various pathways linked with tumor …

We have only recently begun to understand how cancer metabolism affects antitumor
responses and immunotherapy outcomes. Certain immunometabolic targets have been …

Altered cellular metabolism is a hallmark of gliomas. Propelled by a set of recent
technological advances, new insights into the molecular mechanisms underlying glioma …